短暂性脑缺血发作患者脑动脉狭窄与相关危险因素的临床分析  

The clinical analysis of cerebral arteries stenosis and its related risk factors in transient ischemic attack patients

作　　者：王旭[1] 祁宝昌[2] 鞠维娜[1] 

机构地区：[1]吉林大学白求恩第一医院神经内科和神经科学中心,吉林长春130021 [2]吉林大学白求恩第一医院创伤骨科,吉林长春130021

出　　处：《中风与神经疾病杂志》2016年第10期916-919,共4页Journal of Apoplexy and Nervous Diseases

摘　　要：目的短暂性脑缺血发作(TIA)被认为是首次缺血性卒中主要的可控制的危险因素,也是神经科常见急症之一。越来越多的学者提出了应该更加深入认识、研究和总结TIA的相关临床特征以及危险因素,为制定更规范、更有针对性的个体化诊疗策略提供理论依据。方法本研究通过对2010年1月-2013年3月间在吉林大学第一医院住院治疗的1003例TIA患者进行回顾性分析,总结患者的临床特征及脑血管病情况,重点研究患者脑动脉狭窄与各种临床因素、危险因素以及ABCD^2评分的关系,探讨各相关因素对临床的指导意义。结果 TIA患者是否存在血管狭窄与性别、高血压、症状持续时间有相关性(P<0.05),TIA患者血管狭窄分布情况与年龄、糖尿病及ABCD^2评分有相关性(P<0.05)。结论对于短暂性脑缺血患者需要及时对糖尿病、高血压等风险因素进行干预治疗,高度关注TIA症状持续时间,并常规对患者进行ABCD^2评分,减少脑动脉狭窄的发病率,从而减少脑梗死的发生。Objective Transient ischemic attack is believed to be the main controllable risk factor of the first ische-mic stroke and one of the common emergency in neurology department .More and more scholars put forward that we should deeper recognize ,research and summarize the TIA related clinical characteristics and risk factors ,and provide theory basis for formulating more standard and more pointed individualized diagnosis strategy .Methods This study do the retrospective analysis which based on 1003 patients that hospitalization in Jilin university No .1 hospital between January 2010 and March 2013 ,summarized the clinical characteristics and cerebral vascular condition of these patients ,primary study the relationship between cerebral arteries stenosis and every kind of clinical factors ,risk factors,ABCD2 score,discusses the directive signifi-cance of every related factors .Result The presence of cerebral arteries stenosis in TIA patients and gender ,hypertension , duration of symptoms were significant related （P〈0.05）.The distribution of cerebral arteries stenosis in TIA patients and age, diabetes mellitus,ABCD^2 score were significant related （P〈0.05）.Conclusion The timely intervention treatments are necessary for TIA patients who have risk factors ,such as diabetes mellitus and hypertension .Pay much more attention to the duration of symptoms in TIA patients and give the patients an ABCD^2 score routinely .Through above of these to lower the incidence of TIA ,then decrease the occurrence of stroke .

关 键 词：短暂性脑缺血发作 糖尿病 高血压 脑动脉狭窄 ABCD^2评分 

分 类 号：R743.31[医药卫生—神经病学与精神病学]