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出 处:《中国医药导报》2016年第30期118-121,共4页China Medical Herald
基 金:陕西省科技厅社会发展科技攻关项目(2016SF-091)
摘 要:目的 探讨眼眶组织淀粉样变临床特点及误诊原因,探讨其治疗方法。方法 对西安市第四医院2009年1月~2016年1月收治的确诊为眼眶组织淀粉样变12例的临床资料进行回顾性分析,观察患者临床表现、误诊疾病、治疗情况及相关影像学资料。结果 眼眶组织淀粉样变临床症状复杂,眼眶CT及MRI检查无特异性改变。8例误诊为眼眶炎性假瘤,3例误诊为血管瘤,1例误诊为眼睑恶性肿瘤。治疗结果:11例均尽量切除病变,1例病变范围太广,未能全切;术后随诊观察9例,1例放疗,2例进行全身激素治疗。大部分患者预后较好。结论 眼眶组织淀粉样变临床无特征性表现,应依靠病理诊断,不同部位的肿瘤应根据病灶的特点选择合适的诊疗方案,手术应尽可能切除病变组织。Objective To evaluate the clinical characteristics and misdiagnosis reasons of orbital amyloidosis, to discuss the treatment methods. Methods The clinical data of 12 cases diagnosed as orbital amyloidosis admitted to Xi'an No.4 Hospital from January 2009 to January 2016 was analyzed retrospectively. The clinical features, misdiagnosed diseases, treatment situations and related imaging data were observed. Results The clinical symptoms of orbital amyloidosis were complex, the detection of orbital CT and MRI showed no specific changes. There were 8 cases misdiagnosed as orbital inflammatory artificial tumor, 3 cases misdiagnosed as orbital hemangioma, 1 case misdiagnosed as orbital malignancy. The results of treatment: 11 cases were given lesions resection as far as possible, 1 ease failed to take full-cut because of wide lesion range; postoperative follow-up for 9 cases, 1 case took radiation, 2 cases took general hormone therapy. The prognosis of most patients was good. Conclusion The orbital amyloidosis has no characteristic clinical features, the diagnosis of which should depend on pathology, the tumors of different regions should choose appropriate diagnosis and treatment plan according to the characters of the lesions, the operation should cut lesion tissues as much as possible.
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