检测溶液中单分子  

Detecting Single Molecules in Solution

作　　者：刘彦明[1] 刘二保[1] 程介克[1] 

机构地区：[1]武汉大学化学系,武汉430072

出　　处：《分析化学》2002年第8期1000-1004,共5页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金资助项目 (No .2 0 0 750 17)

摘　　要：科学的进步不但要求对物质的整体特征进行鉴定和测定 ,同时还要求对单分子化学和物理性质进行深入探索。在单分子水平对物质进行研究 ,是一项重要的学科前沿交叉领域 ,对分子工程学、分子生物学、分子医学、纳米材料和信息科学具有非常重要的意义。本文评述近年来溶液中单分子检测研究的最新进展 ,包括激光诱导荧光检测、电化学检测及我们最近提出的化学发光检测等。Advances in science require not only the identification and detection of material's ensemble character but also the deep exploration of its single-molecule chemical and physical properties. As a frontier cross-discipline research activity, studying substances at the single-molecule level, is very important to research the molecular engineering, molecular biology, molecular medicine, nanostructured materials and information. The new progress for detecting single-molecule in solution, including laser-induced fluorescence detection, electrochemical detection and chemiluminescence detection, has been reviewed in this paper and the prospects on the frontier of the research area have also been discussed.

关 键 词：单分子检测 激光诱导荧光 电化学 化学发光 分析化学 溶液 

分 类 号：O652[理学—分析化学]