帕金森病睡眠量表中文版在中国西南地区的信效度研究  

Reliability and validity of Parkinson＇s disease sleep scale-Chinese version in the south west of China

作　　者：张锦红[1] 彭蓉[2] 杜宇[4] 牟奕[3] 李楠楠[2] 程兰[5] 

机构地区：[1]四川大学华西保健医院神经内科,成都610064 [2]四川大学华西医院神经内科 [3]四川大学华西医院麻醉实验室 [4]四川大学华西四院急诊科 [5]成都市第一人民医院神经内科

出　　处：《中华医学杂志》2016年第41期3294-3299,共6页National Medical Journal of China

基　　金：四川省卫生厅课题（100387）

摘　　要：目的通过西南地区大样本PD人群对CPDSS进行信效度研究，同时对西南地区PD人群睡眠障碍发生率及睡眠特点初步探讨。方法以544例西南地区PD患者及220例健康人群为研究对象，记录一般特征，同时完成CPDSS、ESS、PDQ39、HAMD、H—Y等量表，运用统计描述、克朗巴赫d系数、组内相关系数、Spearman等级相关系数、Mann—Whitney U检验等对数据进行分析。结果CPDSS的Cronbach’s α 0．79满意；重测信度ICC总分0．94，项目分0．73—0．97；因子分析共提取5个公因子，可解释63．4％的总变异量。PDSS总分和单项分PD组明显低于对照组；西南人群PD睡眠障碍发生率69．3％，高于正常对照人群的29．6％；CPDSS与ESS呈明显负相关；在导致睡眠障碍的因素中日问瞌睡35．9％最常见；西南PD人群睡眠障碍与病程、病情、日常生活质量、抑郁、认知水平、运动症状显著相关。结论CPDSS可行性、信效度良好，是西南地区用于PD患者睡眠评估的得力工具。Objective To evaluate the reliability and validity of Parkinson＇s disease sleep scale- Chinese version （CPDSS） through a study of a large PD population in southwest China, and to explore the prevalence and characteristics of sleep disorders in Parkinson＇s disease （PD） patients from southwest China. Methods A total of 544 PD patients and 220 control subjects were enrolled in our study. Demographic data, CPDSS, ESS, PDQ39, HAMD and H-Y stage were assessed in all subjects. Statistical description, Cronbach＇s alpha coefficient, intra-class correlation coefficient （ICC） , Spearman rank correlation coefficient and Mann-Whitney U test were used for statistical analyses. Result The Cronbaeh＇s alpha coefficient for CPDSS was 0.79, ICC of the total scale was 0.94 and ICC of each item ranged from 0.73 to 0. 97. The factor analysis yielded a five-factor solution, which explained 63.4% of the total variance. Total and each item scores of CPDSS in PD patients were lower than those in healthy controls. 69.3% of PD patients had sleep disorder, while prevalence in the control group was only 29. 6%. Negative correlation was found between CPDSS and ESS. Daytime sleepiness was the most common factor （35.9%） leading to sleep disorders. The sleep disorders of PD patients in Southwest China were significantly related with the course of disease, the severity of disease, the quality of life, depression, cognitive level and motor symptoms. Conclusion CPDSS has good feasibility, reliability and validity in PD population from southwest China. CPDSS is considered as an effective tool for the assessment of sleep disorder in PD patients.

关 键 词：睡眠量表 帕金森病 睡眠障碍 

分 类 号：R742.5[医药卫生—神经病学与精神病学]