注射庆大霉素对梅尼埃病的疗效及对患者听力的影响  

Effect of Injection of Gentamicin in Meniere's Disease and the Impact on the Patients' Hearing

作　　者：王心涛[1] 张克辉[1] 张小安[1] 黄海[1] 王富华[1] 游龙贵[1] 黄振河[1] 

机构地区：[1]江西省赣州市人民医院(南昌大学附属赣州医院),江西赣州341000

出　　处：《中国医学创新》2016年第31期63-66,共4页Medical Innovation of China

摘　　要：目的:探讨注射庆大霉素对梅尼埃病的疗效及对患者听力的影响。方法:选取本院2011年4月-2013年4月收治的80例梅尼埃患者,依据抽签法分为对照组和试验组,每组各40例,对照组患者予以地塞米松治疗,试验组患者予以注射庆大霉素治疗,观察两组患者治疗后的听力变化、眩晕及耳鸣的控制效果,不良反应。结果:治疗后,两组梅尼埃病患者4、8 KHz听阈均有一定降低,但两组比较差异均无统计学意义(P>0.05)。试验组眩晕总有效率90.00%高于对照组72.50%,两组比较差异有统计学意义(P<0.05);试验组耳鸣总有效率67.50%高于对照组45.00%,比较差异有统计学意义(P<0.05),两组患者总不良反应率比较无差异(P>0.05)。结论:射庆大霉素对于梅尼埃病患者的效果确切,能够显著改善患者的眩晕症状,对于耳鸣也有一定的改善效果,同时对于患者的听力影响较小,值得推广。Objective： To study the effect of injection of gentamicin in Meniere＇s disease and the impact on the patients＇ hearing.Method： 80 cases of Meniere＇s disease from April 2011 to April 2013 in our hospital were treated, on the basis of the draw method they were divided into control group and test group, 40 cases in each group, control group was given Dexamethasone therapy, test group was given injection of Gentamicin treatment, two groups＇ after treatment of hearing changes, vertigo and tinnitus control effect and adverse reactions were observed.Result： After treatment, two groups with Meniere＇s disease in 4 and 8 KHz thresholds were reduced to a certain extent, but there were no significant differences between the two groups （P〉0.05） .The test group vertigo total effective rate was 90.00% higher than that of control group 72.50%, the difference was statistically significant （ P〈0.05 ） ; the test group total dizziness efficiency of 67.50% higher than that of control group 45.00%, the difference was statistically significant （ P〈0.05 ） .Total adverse reaction rate was no difference between two groups （P〉0.05） .Conclusion： Shoot for gentamicin in patients with Meniere＇s disease effect, can significantly improve patients with symptoms of dizziness, to the improvement of the tinnitus also to have certain effect, and the effect of hearing for the patient is less, it is worthy of promoting.

关 键 词：梅尼埃病 庆大霉素 疗效 听力 

分 类 号：R764.33[医药卫生—耳鼻咽喉科]