A Selective and Sensitive Fluorescence Probe for Se（IV） Based on Fluorescence Quenching of Gatifloxacin  

作　　者：LIU Qing HUAN Yanfu ZHENG Qingchuan FEI Qiang FEI Yanqun FAN Qian FENG Guodong SHAN Hongyan 

机构地区：[1]College of Chemistry, Jilin University, Changchun 130021, P. R. China [2]Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130021, P. R. China [3]Changchun WeiersaiBiotec Pharmaceutical Co., Ltd., Changchun 130616, P. R. China [4]Changchun Vocational Institute of Technology, Changchun 130033, P. R. China

出　　处：《Chemical Research in Chinese Universities》2016年第5期736-741,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China（No.21207047）, the State Major Project for Science and Technology Development, China（No.2013YQ47078102-3）, the Science-Technology Development Project of Jilin Province of China（Nos.20130206014GX, 20140623007TC, 20150204017YY）, the Open Project of the State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, China（No.2014-07） and the Natural Science Foundation of Jilin Province, China（No.20160101314JC）.

摘　　要：A novel high selective and sensitive fluorescence probe termed gatifloxacin was discovered based on fluorescence ＂on-off＂ phenomenon in the presence of Se（IV）. In the Tris-HCl/acetonitrile（3：7, volume ratio, Tris-HCl 0.05 mol/L, pH=7.3） system, the fluorescence intensity of gatifloxacin was linearly decreased with the concentration increase of Se（IV） in a range of 1.0×10-5--5.0×10-5 mol/L with a correlation coefficient of 0.9979（R2=0.9958） and in a range of 5.0×10-5--1.0 ×10-4 mol/L with a correlation coefficient of 0.9973（R2=0.9946）. The detection limit of Se（IV） was 1.70×10-6mol/L.A novel high selective and sensitive fluorescence probe termed gatifloxacin was discovered based on fluorescence ＂on-off＂ phenomenon in the presence of Se（IV）. In the Tris-HCl/acetonitrile（3：7, volume ratio, Tris-HCl 0.05 mol/L, pH=7.3） system, the fluorescence intensity of gatifloxacin was linearly decreased with the concentration increase of Se（IV） in a range of 1.0×10-5--5.0×10-5 mol/L with a correlation coefficient of 0.9979（R2=0.9958） and in a range of 5.0×10-5--1.0 ×10-4 mol/L with a correlation coefficient of 0.9973（R2=0.9946）. The detection limit of Se（IV） was 1.70×10-6mol/L.

关 键 词：GATIFLOXACIN Fluorescence probe QUENCHING SELENIUM 

分 类 号：O[理学]