GATIFLOXACIN

作品数：25被引量：100H指数：4
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相关领域：医药卫生更多>>
相关作者：朱琪刘燕王彤刘健李家泰更多>>
相关机构：北京大学第一医院中国药科大学河南大学北京协和医学院更多>>
相关期刊：《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《Chemical Research in Chinese Universities》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Nonlinear impacts of temperature on antibiotic resistance in Escherichia coli
《Environmental Science and Ecotechnology》2024年第6期339-343,共5页Wenya Zhao Shikan Zheng Chengsong Ye Jianguo Li Xin Yu 
National Natural Science Foundation of China(U2005206);National Key R&D Program of China(2023YFE0112100).
The increase in bacterial antibiotic resistance poses a significant threat to the effectiveness of antibiotics,and there is growing evidence suggesting that global warming may speed up this process.However,the direct ...
关键词：Antibiotic resistance TEMPERATURE GATIFLOXACIN Resistance evolution Fitness costs 
Reactive species regulation by interlayered Na^(+)/H^(+)of titanate nanotubes decorated Co(OH)_(2)hollow microsphere for peroxymonosulfate activation and gatifloxacin degradation
《Chinese Chemical Letters》2023年第12期263-268,共6页Bin Zhou Long Chen Fan Li Weiliang Sun Zhicheng Pan Yumei Peng Lian Qiu Wen Liu 
financially supported by the National Key Research and Development Program of China(No.2021YFA1202500);National Natural Science Foundation of China(NSFC)(Nos.52270053,52200083and 52200084);Beijing Nova Program(No.20220484215);China Postdoctoral Science Foundation(No.2021M700213);the Key Special Projects for Science and Technology of Inner Mongolia(No.2021EEDSCXSFQZD001);Emerging Engineering Interdisciplinary-Young Scholars Project,Peking University,the Fundamental Research Funds for the Central Universities.
Emerging organic pollutants(EoPs)in water are of great concern due to their high environmental risk,so urgent technologies are needed for effective removal of those pollutants.Herein,a heterogeneous advanced oxidation...
关键词：Heterogeneous catalysis Peroxymonosulfate activation Sulfate radical Singlet oxygen Antibiotic 
A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis被引量：4
《Bioactive Materials》2023年第2期271-285,共15页Mengna Li Jing-Wei Xu Jiayong Li Wei Wang Chenqi Luo Haijie Han Zhi-Kang Xu Ke Yao 
the Program of National Natural Science Foundation of China[81870641,82070939];Key Research and Development Program of Zhejiang Province of China[2020C03035].
Postoperative endophthalmitis(POE)has been the most threatening complication after cataract surgery,which perhaps can be solved by the antibiotic-loaded intraocular lens(IOL).However,most drug-loaded IOLs demonstrate ...
关键词：PHOTOCURING Drug delivery intraocular lens 3D printing Postoperative endophthalmitis GATIFLOXACIN 
Antimicrobial Effects of Gatifloxacin on Canine Periodontopathic Bacteria In Vitro
《Journal of Biomedical Science and Engineering》2022年第2期89-96,共8页Tadashi Miura Yukari Oda Koji Tanabe Yasuhiko Shizawa Taichi Ito Longqiang Yang 
The aim of this study was to identify the potential antibacterial effects of gatifloxacin on one of canine periodontal pathogens, Porphyromonas gulae. The minimum inhibitory concentrations (MIC) of gatifloxacin and it...
关键词：Periodontal Disease ANTIBIOTICS DOG Porphyromonas gulae Veterinary Medicine 
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways
《International Journal of Ophthalmology(English edition)》2019年第10期1524-1530,共7页Bin Xu Yun-Long Sui Ting-Jun Fan 
Supported by the National High Technology R&D Program of China(No.2006AA02A132)
AIM: To reveal the cytotoxicity and related mechanisms of gatifloxacin(GFX) to stromal fibroblasts(SFs) in vitro.METHODS: SFs were treated with GFX at different concentrations(0.009375%-0.3%), and their viability was ...
关键词：GATIFLOXACIN STROMAL FIBROBLASTS cytotoxicity apoptosis CASPASE EXTRINSIC PATHWAY intrinsic PATHWAY 
A Selective and Sensitive Fluorescence Probe for Se（IV） Based on Fluorescence Quenching of Gatifloxacin
《Chemical Research in Chinese Universities》2016年第5期736-741,共6页LIU Qing HUAN Yanfu ZHENG Qingchuan FEI Qiang FEI Yanqun FAN Qian FENG Guodong SHAN Hongyan 
Supported by the National Natural Science Foundation of China（No.21207047）, the State Major Project for Science and Technology Development, China（No.2013YQ47078102-3）, the Science-Technology Development Project of Jilin Province of China（Nos.20130206014GX, 20140623007TC, 20150204017YY）, the Open Project of the State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, China（No.2014-07） and the Natural Science Foundation of Jilin Province, China（No.20160101314JC）.
A novel high selective and sensitive fluorescence probe termed gatifloxacin was discovered based on fluorescence ＂on-off＂ phenomenon in the presence of Se（IV）. In the Tris-HCl/acetonitrile（3：7, volume ratio, Tri...
关键词：GATIFLOXACIN Fluorescence probe QUENCHING SELENIUM 
Potential Antimicrobial Effects of Gatifloxacin on Periodontopathic Bacteria in Vitro被引量：1
《Journal of Biomedical Science and Engineering》2016年第7期354-359,共6页Tadashi Miura Koji Tanabe Eri Tsukagoshi Koichi Kida Yasuhiko Shizawa Nahoko Miyake Masataka Kasahara Masao Yoshinari 
The aim of this study was to identify the potential antibacterial effects of gatifloxacin on periodontal pathogens including Aggregatibacter actinomycetemcomitans, Porphyromonas gingi-valis, and Prevotella intermedia....
关键词：Local Administration PERI-IMPLANTITIS Periodontopathic Bacteria Antimicrobial Activity GATIFLOXACIN 
Design and development of novel bioadhesive niosomal formulation for the transcorneal delivery of anti-infective agent:In-vitro and ex-vivo investigations被引量：4
《Asian Journal of Pharmaceutical Sciences》2015年第4期322-330,共9页Yahaya Zubairu Lalit Mohan Negi Zeenat Iqbal Sushama Talegaonkar 
Gatifloxacin eye drops are frequently used in eye infections.However such formulations have a major drawback i.e.short duration of action and usually require 4e6 times installations daily.A chitosan coated niosomal fo...
关键词：OCULAR NIOSOMES BIOADHESIVE Chitosan Fluorescence GATIFLOXACIN 
Preparative Resolution of Gatifloxacin Enantiomers with Pre-Column Esterification Strategy and Comparing Their Enantioselectivity to Bacteria and Antibody被引量：1
《Biomedical and Environmental Sciences》2015年第2期157-160,共4页ZHANG Chi Jian LEI Hong Tao HUANG Xiao Long LIU Ying Ju CAI Kai XU Zhen Lin SUN Yuan Ming 
supported by Guangdong Natural Science Foundation(S2013030013338);the Ph D.Programs Foundation of Ministry of Education of China(20114404130002);Guangdong Planed Program in Science and Technology(cgzhzd0808,2013B051000072,2012A020100002)
Gatifloxacin （GFX） is a kind of chiral fluoroquinolones compound due to the methyl group at the C-3 position of the piperazine ring[1]. Although the enantiomers of GFX show similar levels of antimicrobial activity a...
关键词：Preparative Resolution of Gatifloxacin Enantiomers with Pre-Column Esterification Strategy and Comparing Their Enantioselectivity to Bacteria and Antibody DEA than 
Pulse radiolysis study on gatifloxacin——A fluoroquinolone antibiotic被引量：3
《Science China Chemistry》2012年第7期1358-1363,共6页LI HaiXia LIU YanCheng TANG RuiZhi ZHANG Peng FU HaiYing YAO SiDe WANG WenFeng 
supported by the National Natural Science Foundation of China (21173252)
The reactions between gatifloxacin(GFX) and various one-electron oxidants,such as ˙OH,N3˙,Br2˙ˉ,and SO4˙ˉ,have been studied by pulse radiolysis techniques.The GFX radical anion formed in the reaction of GFX with...
关键词：GATIFLOXACIN pulse radiolysis radical anion radical cation 
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