不同材料PFM对患者牙周组织、龈沟液中炎症因子水平的影响  

Effect of PFM with Different Materials on the Levels of Inflammatory Factors in Periodontal Tissue and Gingival Crevicular Fluid of Patients

作　　者：杨甜甜[1] 龚正林[1] 

机构地区：[1]陕西省安康市中心医院,陕西安康725000

出　　处：《医学临床研究》2016年第10期1926-1928,共3页Journal of Clinical Research

摘　　要：[目的]探讨不同材料的烤瓷熔附金属全冠（PFM）修复后对患者牙周组织、龈沟液中炎症因子水平的影响。[方法]选取本院2013年1月至2015年6月接受牙修复的患者60例，根据修复材料分为：镍铬合金烤瓷冠修复（A组）、镍铬合金镀金烤瓷冠修复（B组）、金沉积烤瓷冠修复（C组）各20例，测定三组患者修复前、修复后6个月的龈沟液量（GCF）、龈沟探诊深度（GCD）、牙龈指数（GI）、龈沟液中肿瘤坏死因子-α（TNF-α）、白细胞介素-1β（IL-1β）、白细胞介素-6（IL-6）、白细胞介素-8（IL-8）的水平。[结果]修复前，A组、B组和C组患者的GCF、GCD、GI指数差异均无统计学意义（P〉0．05）；修复6个月后复查，A组患者的GCF、GCD、GI指数较修复前显著升高（P〈0．05），A组患者的GCF、GCD、GI指数显著高于B组和C组患者（P〈0．05）；修复前，A组、B组和C组患者龈沟液中TNF-α、IL-1β、IL-6、IL-8的水平差异均无统计学意义（P〉0．05）；修复6个月后复查，A组患者的TNF-α、IL-1β、IL-8的水平较修复前显著升高（P〈0．05），A组患者的TNF-α、IL-1β、IL-8水平显著高于B组和C组患者（P〈0．05）。[结论]镍铬合金烤瓷冠对患者的牙周组织影响更为明显，患者牙龈沟液中炎症反应因子水平更高。[Objective]T0 investigate the effects of porcelain fused to metal crown （PFM） of different materials on the levels of inflammatory factors in periodontal tissue and gingival sulcus, EMethods]A total of 60 patients who underwent dental restoration were selected from January 2013 to June 2015 and divided according to the repairing materials into group A （nichrome procelain crowns）, group B （nickel-chrome gold-plated porcelain fused-to-metal crowns） and group C （gold-deposited porcelain crowns）, with 20 cases in each group. The amount of Gingival crevicular fluid （GCF）, sulcus probing depth （GCD）, gingival index （GI） and tumor necrosis factor （TNF-α） alpha in gingival crevicular fluid were measured before and 6 months after repair. Interleukin -1 beta （IL-1β）, interleukin -6 （IL-6） and interleukin -8 （IL-8） level were measured. [Results]Before restoration, A group, B group and C group showed no significant difference in GCF, GCD and GI indexes （ P 〉0.05）. Six months after repair, the GCF, GCD, and GI indexes of patients in the A group were significantly increased （ P 〈0.05）; they were significantly higher than those of B group and C group （ P 〈0.05）. Before restoration, differences in the levels of TNF-α, IL-1β, IL-6 and IL-8 in gingival crevicular fluid of patients in A group, B group and C group had no statistical significance （ P 〉0.05）;6 months after repair, TNF-α, IL-1 beta and IL-8 levels in patients in the A group were significantly increased compared to before restoration （ P〈0.05） and were significantly higher than those of B group and C group （ P 〈0.05）. [Conclusion]The impact of nichrome alloy PFM on periodontal tissue in patients is more pronounced with higher levels of inflammatory factors in GCF.

关 键 词：牙科材料 金属烤瓷合金 牙周组织 牙龈缝液 肿瘤坏死因子α 白细胞介素类 

分 类 号：R781.4[医药卫生—口腔医学]