红细胞分布宽度对无症状性脑卒中的预测价值  

Predictive value of red blood cell distribution width to cryptogenic stroke

作　　者：朱永娟 姜健 黄昌华 陈小波 ZHU Yong-juan JIANG Jian HUANG Chang-hua CHEN Xiao-bo(Clinical Laboratory,Qilinshan Sanatorium, Shenzhen, Guangdong 518055, China)

机构地区：[1]深圳市麒麟山疗养院检验科,广东深圳518055 [2]深圳市福田区中医院检验科,广东深圳518034 [3]深圳市麒麟山疗养院体检中心,广东深圳518055

出　　处：《中国卫生检验杂志》2016年第20期2967-2969,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨红细胞分布宽度(RDW)对无症状性脑卒中(CS)患者的预测价值。方法选择2013年1月-2015年12月深圳市麒麟山疗养院诊断为CS的71名患者作为疾病组,以同期来院体检的60例健康者作为对照组。收集2组对象的一般人口学数据、躯体疾病诊断等资料,抽取外周血检测血常规、血糖、血脂、血清铁、CRP、FIB等指标。结果疾病组肥胖人数比、BMI、RDW、RDW≥14%比例、WBC、CRP高于对照组,差异有统计学意义(P<0.05),其他各指标组间差异无统计学意义(P>0.05)。ROC曲线显示,RDW对于CS的诊断具有较高的敏感度(69.01%)。非条件Logistic回归分析显示,仅RDW≥14.58%为CS的独立预测指标(OR=1.726,P<0.05)。结论 RDW对于独立预测无症状性脑卒中有一定的临床价值。Objective To explore the predictive value of red blood cell distribution width（ RDW） in patients with cryptogenic stroke（ CS）. Methods A total of 71 CS patients and 60 healthy controls were collected as the patients group and the control group respectively from Qilinshan Sanatorium from January 2013 to December 2015. Demographic and physical diseases data were collected for tests of routine blood（ including RDW）,glucose,lipids,iron,C- reactive protein（ CRP）,fibrinogen（ FIB）,etc. Results Proportion of obese,BMI,RDW,RDW≥14%,WBC and CRP were higher in CS patients than in the controls,with the differences statistically significant（ P 〈 0. 05）. There was no statistical significance on the difference in other markers between the 2 groups（ P 〉0. 05）; RDW had a high sensitivity（ 69. 01%） in the diagnosis of CS according to the ROC curve.Based on logistic regression analysis,RDW≥14. 58% was the only predictor independently associated with cryptogenic stroke（ OR = 1. 726,P 〈 0. 05）. Conclusion RDW may play a role in predicting cryptogenic stroke independently.

关 键 词：无症状性脑卒中 红细胞分布宽度 炎症 红细胞参数 

分 类 号：R743.3[医药卫生—神经病学与精神病学]