3033张血液科门诊处方超说明书用药调查与分析  

Investigation and Analysis on Off-label Drug Use in 3033 Outpatient Prescriptions of Internal Hematology

作　　者：周鹏[1] 张秀琳[2] 邹顺[1] 

机构地区：[1]昆明医科大学第二附属医院药学部,云南昆明650101 [2]昆明医科大学药学院,云南昆明650500

出　　处：《中国医院用药评价与分析》2016年第10期1422-1424,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解昆明医科大学第二附属医院(以下简称"我院")血液科门诊超说明书用药情况,为促进临床合理规范用药提供参考。方法:抽取2014年6月—2015年6月我院血液科门诊处方3 033张,参考药品说明书,对处方中药物的适应证、给药频次、给药剂量、年龄、禁忌证和给药途径等进行逐一核对,判断并分析超说明书用药情况。结果:抽取的3 033张处方中,共3 229条用药记录,其中超说明书用药2 012条(占62.31%)。超说明书用药中,超说明书适应证用药最为常见,占超说明书用药记录总数的98.61%(1 984条),其次分别为超说明书给药频次用药、超说明书剂量用药。结论:我院血液科门诊处方超说明书用药现象较普遍,应对其进行密切监测和适当干预,使用药尽快规范化。OBJECTIVE： To investigate the off-label drug use in outpatient prescriptions of internal hematology in the Second Affiliated Hospital of Kunming Medical University（ hereinafter referred to as ＂our hospital ＂）,so as to provide reference for the rational standard drug use in clinic. METHODS： 3 033 outpatient prescriptions of internal hematology from Jun. 2014 to Jun. 2015 were extracted,and prescriptions for indications,administration frequency,administration doses,age,contraindications and route of administration were analyzed one by one about off-label drug use according to drug instructions. RESULTS： Of the 3 033 prescriptions,a total of 3 229 drug prescriptions in the outpatient prescriptions of internal hematology were selected,among which off-label drug use was 2 012 cases（ 62. 31%）. Of the off-label drug use cases,off-label drug use indications was the most common,accounting for98. 61%（ 1 984 cases） of the total off-label drug use outpatient prescriptions,followed by medication for overfrequency and over-dosage. CONCLUSIONS： Off-label drug use in outpatient prescriptions is a common phenomenon our hospital; therefore,it is necessary to attach more importance to the phenomenon by the close monitoring and proper intervention,so as to promote the standardization of drug use.

关 键 词：超说明书用药 血液科 门诊 调查分析 

分 类 号：R97[医药卫生—药品]