神经节苷脂钠治疗重症脑卒中患者的效果分析及对白细胞介素的影响  

Therapeutic effect of gangliosides in treatment of severe stroke and its influence on serum interleukins

作　　者：梁添书 刘志华[1] 赖旻瑶[1] 丘鸿凯[1] 

机构地区：[1]南方医科大学附属中山市博爱医院神经内科,广东中山528403

出　　处：《中国医药科学》2016年第17期75-77,共3页China Medicine And Pharmacy

摘　　要：目的 本研究对神经节苷脂钠治疗重症脑卒中患者的效果分析及对白细胞介素的影响进行研究,为临床治疗提供参考。方法 对本院2011年6月~2015年12月期间诊治的重症脑卒中患者进行研究,分析神经节苷脂钠的治疗效果及对白细胞介素的影响。结果 研究发现神经节苷脂钠治疗重症脑卒中患者NIHSS评分明显降低（P〈0.05）,免疫球蛋白、白细胞介素及BNP、CRP和Hcy蛋白水平明显降低（P〈0.05）。结论 神经节苷脂钠对重症脑卒中患者有明显的效果,且可能与其调控白细胞介素及C反应蛋白有关。Objective To explore the therapeutic effect of gangliosides in treatment of severe stroke patients and its influence on serum interleukins. Methods 120 cases of severe stroke patients cured in our hospital from Jun 2011 to Dec 2015 were enrolled in this part. The effect of gangliosides in treatment of severe stroke and its influence on serum interleukins were detected. Results The results showed that the NIHSS scores were decreased greatly （P 〈 0.05） after the medication of gangliosides. At the meaning time, the serum IgA, IgM, IgG, IL-2, IL-3, IL-6 and BNP, CRP, Hcy concentration were decreased greatly（P 〈 0.05） after the treatment of gangliosides. Conclusion Gangliosides exerts a significant effect on severe stroke, which is related with the regulation on serum interleukins.

关 键 词：神经节苷脂钠 重症脑卒中 白细胞介素 C反应蛋白 脑钠肽 

分 类 号：R743[医药卫生—神经病学与精神病学]