星蒌承气汤对急性脑缺血SIRS期患者血清D-乳酸水平的影响  

Effect of XingLou ChengQi Decoction on Serum D-lactate Level of the Patients with Acute Cerebral Ischemia at SIRS stage

作　　者：王威[1] 

机构地区：[1]北京中医药大学第三附属医院,北京100029

出　　处：《西部中医药》2016年第10期100-102,共3页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察星蒌承气汤对急性脑缺血患者全身炎症反应综合征(SIRS)期患者血清D-乳酸(D-L)水平的影响,探讨通腑化痰法改善肠黏膜屏障功能的疗效机制。方法:将108例患者随机分为观察组72例、对照组36例。2组均给予西医综合治疗,观察组同时口服星蒌承气汤,2组均连续治疗1周。观察2组治疗前后症状与体征评分及血清D-L水平的变化情况。结果:症状与体征评分及血清D-L观察组治疗前后比较,差异有统计学意义(P<0.05),对照组治疗前后比较,差异无统计学意义(P>0.05),治疗后2组间比较差异有统计学意义(P<0.05)。结论:星蒌承气汤可有效降低急性脑缺血SIRS期患者症状与体征评分及血清D-L水平。Objective： To explore the therapeutic mechanism of relaxing the bowels and resolving phlegm method in improving intestinal mueosal barrier function by observing the effect of XingLou ChengQi decoction on the serum D-lactate （D-L） level of patients with acute cerebral ischemia in the systemic inflammatory response syn- drome（SIRS） stage. Method： All 108 cases were randomly divided into the observation group （72 cases） and the con- trol group （36 cases）. Both groups were treated with comprehensive western medicine, at the same time the observa- tion group was given XingLou ChengQi decoction, both groups were treated for one week consecutively. The symp- toms, signs score and changes of the serum D-L level were observed before and after the treatment. Results： About the symptoms, signs score and changes of the serum D-L level of the observation group before and after the treat- ment, the differences were significant （P〈0.05）. And there was no big difference in the control group before and af- ter the treatment （P〉0.05）. After the treatment, the difference between the two groups were significant （P〈0.05）. Conclu- sion： XingLou ChengQi decoction can effectively reduce the symptoms, signs score and the serum D-L level of pa- tients with acute cerebral ischemia in the SIRS stage.

关 键 词：通腑化痰法 急性脑缺血 血清D-乳酸 

分 类 号：R743.3[医药卫生—神经病学与精神病学]