步长脑心通胶囊对急性脑梗死患者血浆脂蛋白磷酯酶A2水平的影响  

Effect of Buchang Naoxintong capsules on plasma lipoprotein-associated phospholipase A2 level in acute cerebral infarction

作　　者：文学 林进光 梁健 林涛 陈志健 罗德宏 陈伟明 

机构地区：[1]广东省阳江市人民医院,广东阳江529500

出　　处：《广东医学院学报》2016年第4期409-411,共3页Journal of Guangdong Medical College

基　　金：广东省中医药局项目基金(No.20141293)

摘　　要：目的观察步长脑心通胶囊对急性脑梗死患者不同时期血浆脂蛋白磷脂酶A2(Lp-PLA2)水平的影响。方法116例急性脑梗死患者随机分为对照组(56例)和观察组(60例),对照组采用常规疗法,观察组加用步长脑心通胶囊。监测两组患者治疗后1、2、4、8、12周的血浆Lp-PLA2水平。结果治疗后两组上述观察时期血浆Lp-PLA2水平均低于治疗前,且观察组显著低于对照组,差异均有统计学意义(P<0.01)。结论步长脑心通胶囊治疗急性脑梗死可降低血浆Lp-PLA2水平。Objective To observe the effect of Buchang Naoxintong capsules on plasma lipoprotein-associated phospholipase A2 （Lp-PLA2） level in acute cerebral infarction （ACI）. Methods A total of 116 ACI patients were randomized to control and treatment groups, each receiving conventional treatment and plus Buehang Naoxintong capsules. Plasma Lp-PLA2 content was determined after 1, 2, 4, 8, and 12 weeks. Results Plasma Lp-PLA2 level was remarkably decreased at all time points after treatment in both groups, especially in treatment group （P〈0.01）. Conclusion Buchang Naoxintong capsules can reduce plasma Lp-PLA2 level in ACI patients.

关 键 词：急性脑梗死 步长脑心通胶囊 脂蛋白磷脂酶A2 

分 类 号：R743[医药卫生—神经病学与精神病学]