术中应用A群链球菌制剂预防乳腺癌根治术后皮下积液的疗效观察  

Clinical Observation on the Effect of Group A Streptococcus Preparation in the Treatment of Subcutaneous Effusion After Radical Mastectomy

作　　者：祖健[1] 陈楚吟[1] 胡美霞[1] 廖艳华[1] 严金凤[1] 曾庆兰[1] 翟青[1] 

机构地区：[1]广东省人民医院肿瘤中心乳腺科,广东广州510080

出　　处：《中国继续医学教育》2016年第31期174-176,共3页China Continuing Medical Education

摘　　要：目的观察沙培林在乳腺癌根治术中局部浸泡对术后皮下积液的预防疗效。方法随机抽取120例乳腺癌患者加入本次实验,所有患者通过术前评估后,行乳腺癌改良根治术或保乳根治术,术中清扫腋窝淋巴结后注射用水冲洗伤口,实验组60例接受沙培林20 g溶于10ml生理盐水浸泡30 min,对照组60例术中未接受药物治疗。术后观察两组患者的引流量及拔管时间,评价疗效。结果实验组患者术后伤口引流量少于对照组,留置引流管时间短于对照组。副反应发生率与对照组相当。结论乳腺癌根治术中局部应用沙培林可有效减少引流管留置时间及引流量,预防皮下积液的发生。Objective To observe Sha Peilin in radical mastectomy for breast cancer prevention effect of partial immersion subcutaneous effusion after operation. Methods A random sample of 120 cases of breast cancer patients participate in this study, all patients with preoperative evaluation after underwent modified radical mastectomy or breast conserving surgery, intraoperative axillary lymph node dissection after injection water wash the wound, 60 cases in the experimental group received 20 g sapylin dissolved in 10 ml of normal saline soak 30 min control drug treatment did not accept the group in 60 cases. Postoperative observation of the two groups of patients with drainage volume and extubation time, evaluation of curative effect. Results Patients in the experimental group were less than the control group, the time of indwelling drainage tube was shorter than that of the control group. The incidence of side effects was comparable to that of the control group. Conclusion It can effectively reduce the time of drainage tube and drainage operation in the local application of sand forest of breast cancer, prevent the occurrence of subcutaneous effusion.

关 键 词：乳腺癌 沙培林 皮下积液 

分 类 号：R737.97[医药卫生—肿瘤]