石墨烯-聚乙烯醇-钯复合物的制备及在克林沙星检测中的应用  

Synthesis and application of graphene-polyvinyl alcohol-Pd nanocomposite in the determination of clinafloxacin

作　　者：张羽[1] 陈宏[1,2,3] 赵刚[1,2,3] 张文婷[1] 薄乐[1] 励建荣[2,3] ZHANG Yu CHEN Hong ZHAO Gang ZHANG Wen-ting BO Le LI Jian-rong(College of Chemistry and Chemical Engineering,Bohai University, Jinzhou 121013 , China College of Food Science and Technology,Bohai University,Jinzhou,121013 ,China National＆Local Joint？ Engineering Research Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic, Products, Jinzhou 121013 , China)

机构地区：[1]渤海大学化学化工学院,辽宁锦州121013 [2]渤海大学食品科学与工程学院,辽宁锦州121013 [3]生鲜农产品贮藏加工及质量安全控制技术国家地方联合工程技术研究中心,辽宁锦州121013

出　　处：《化学研究与应用》2016年第11期1593-1598,共6页Chemical Research and Application

基　　金："十二五"国家科技支撑计划(2012BAD29B06)资助;辽宁省科技厅攻关项目(2015103020)资助

摘　　要：用石墨烯-聚乙烯醇-钯修饰电极（GN-PVA-Pd/GCE）测定水产品中的克林沙星（CFN）。研究了CFN在GN-PVA-Pd/GCE上的电化学行为,并探讨了示差脉冲伏安法检测CFN的可行性。结果表明,在pH=10、扫速=100m V·s^-1的条件下,GN-PVA-Pd/GCE修饰电极对CFN的响应效果最好,检测CFN的线性范围分为两段,在0.09-5.4μM CFN浓度区间,峰电流与CFN浓度的线性关系为I（μA）=0.998 CCFN（μM）＋0.034;在5.4-72μM CFN浓度区间,线性关系为I（μA）=0.207CCFN（μM）＋4.154。检出限为0.03μM（信噪比S/N=3）。GN-PVA-Pd/GCE用于检测水产品中CFN,加标回收率为96.7%-106.6%,RSD为2.8%-3.9%。Graphene-polyvinyl alcohol-Pd（ GN-PVA-Pd） nanocomposite was synthesized and applied to the determination of clinafloxacin（ CFN）. The electrochemical behavior of CFN on the nanocomposite was investigated and a differential pulse voltammetry method was developed for the determination of CFN.The results showed that the peak current increased with the CFN concentration in the range of 0. 09 - 5. 4μM with a calibration equation of I（ μA） = 0. 998CCFN＋0. 034（ μM） and in the range of 5. 4 - 72μM with a calibration equation of I（ μA） = 0. 207CCFN＋4. 154（ μM） under the conditions of p H 10 and scan rate 100 m V·s^-1. The detection limit was estimated to be 0. 03μM（ S / N = 3）. The modified electrode has been applied to the determination of CFN in aquatic product samples with the recoveries of 96. 7% - 106. 6%.

关 键 词：石墨烯 聚乙烯醇 钯纳米粒子 电分析 克林沙星 

分 类 号：O657.1[理学—分析化学]