肠易激综合征症状与肠道气体的研究进展  

Progress in Study on Symptoms of Irritable Bowel Syndrome and Intestinal Gas

作　　者：李佩[1,2] 张少波[1,2] 苏军凯[1] 刘妍[1] 张鸣青[1,2] 

机构地区：[1]厦门大学附属东南医院(解放军第175医院)消化内科南京军区消化内镜中心,363000 [2]福建中医药大学

出　　处：《胃肠病学》2016年第10期629-632,共4页Chinese Journal of Gastroenterology

基　　金：吴阶平医学基金会资助项目(320.6750.15231)

摘　　要：肠易激综合征(IBS)是临床较常见的慢性功能性肠道疾病,在我国发病率呈逐年上升趋势。目前IBS病因和发病机制仍未完全阐明,可能与肠道气体有关。肠道气体通常由59%N_2、21%H_2、9%CO_2、7%甲烷(CH_4)以及4%O_2组成,其中H_2和CH_4仅由肠道细菌代谢产生。IBS患者常表现为腹胀等肠胀气症状,提示存在肠道积气。近年来,IBS症状与肠道气体的关系备受关注,本文就IBS症状与肠道气体的研究进展作一综述。Irritable bowel syndrome（ IBS） is a commonly seen chronic functional bowel disease,the prevalence showed a rising trend in recent year in China. At present,the etiology and pathogenesis of IBS have not yet been fully elucidated,and may be related to intestinal gas. Intestinal gas is usually composed of 59% N_2,21% H_2,9% CO_2,7%methane（ CH_4） and 4% O_2,in which H_2 and CH_4 are produced only by intestinal bacteria metabolism. IBS patients usually manifested as having abdominal distension and symptoms of flatulence,suggesting the occurrence of accumulation of intestinal gas. In recent years,the relationship between symptoms of IBS and intestinal gas has attracted much attention.This article reviewed the progress in study on symptoms of IBS and intestinal gas.

关 键 词：肠易激综合征 肠胃胀气 甲烷 肠道气体 肠道微生态 

分 类 号：R574[医药卫生—消化系统]