胸膜外孤立性纤维瘤影像学表现及病理学特征  

Image menifestations and pathological features of extrapleural solitary fibrous tumor

作　　者：鲍亚星[1] 张伟[2] 

机构地区：[1]无锡市第五人民医院放射科,江苏省214000 [2]南京医科大学第一附属医院放射科

出　　处：《江苏医药》2016年第21期2312-2314,F0003,I0001,共5页Jiangsu Medical Journal

基　　金：江苏高校优势学科建设工程资助项目(JX10231801)

摘　　要：目的探讨胸膜外孤立性纤维瘤(ESFT)影像学表现及其病理学特征。方法回顾性分析6例经病理证实的ESFT的CT和MRI表现,并将影像学表现与病理组织学和免疫组化结果相对照。结果 ESFT发生在小脑、食管、眼眶、盆腔各1例,后腹膜2例。CT表现为圆形或卵圆形肿块,边界较清楚,3例密度均匀,2例密度不均匀。MRI表现为T1WI呈低或等信号,T2WI呈高、低混杂信号。增强后肿瘤呈"渐进性"及"地图样"强化。病理学检查肿瘤细胞呈梭形、卵圆形、圆形,免疫组化CD34及Vimentin均表达阳性。结论 ESFT是一种少见的间叶源性软组织肿瘤,影像学表现不典型,确诊需靠病理学及免疫组化检查。Objective To discuss the image extrapleural solitary fibrous tumor （ESFT）. Methods menifestations and pathological features of The data of CT and MRI of 6 patients with ESFT were retrospectively analyzed, which were compared with pathological results. Results The ESFT was found in the cerebellum in 1 case, in the esophagus in 1 case, in orbit in 1 case, in pelvic cavity in 1 case, and in posterior peritoneum in 2 cases. CT showed a solitary round or oval well circumscribed mass in all 6 cases,of whom 3 cases were with homogeneous density and 2 cases with heterogeneous density. The tumor demonstrated homogeneously low or isointense signal on T1WI and mixed low and high signal on T2WI. Gradual and geographic enhancement of the tumor was identified on postcontrast images. Pathological examination showed that the tumors were spindle shaped, oval and round, which were positive for CD34 and Vimention examined by immunohistochemistry. Conclusion ESFT is rare soft tissue tumor originated from mesenchyma without typical imaging features. The accurate diagnosis of ESFT needs histopathological and immunohistochemical examinations.

关 键 词：孤立性纤维瘤 

分 类 号：R730[医药卫生—肿瘤]