经颈静脉肝内门体分流术在肝癌伴门脉癌栓中的临床应用  

Clinical application of transjugular intrahepatic portosystemic shunt in hepatocellular carcinoma with portal vein tumor thrombosis

作　　者：谢正元[1] 熊恺[1] 郭武华[1] XIE Zheng-yuan XIONG Kai GUO Wu-hua.(Department of Gastroenterology,Second Affiliated Hospital,Nanchang University, Nanchang 330006, Chin)

机构地区：[1]南昌大学第二附属医院消化内科,南昌330006

出　　处：《放射学实践》2016年第11期1089-1092,共4页Radiologic Practice

基　　金：江西省卫生计生委科技计划项目(20151076)

摘　　要：目的:回顾分析并探讨经颈静脉肝内门体分流术(TIPS)在原发性肝癌伴门静脉癌栓(PVTT)治疗中的应用价值。方法:回顾分析原发性肝癌伴门静脉癌栓,并接受TIPS手术治疗的患者的病例资料,了解术后主要症状改善情况,并发症及生存期等随访资料。结果:接受TIPS手术的肝癌伴PVTT患者共13例,其中成功进行手术患者10例。3例上消化道出血患者成功止血,7例腹水患者中的5例腹水减少,手术成功患者的平均生存期为(112.1±41.7)天,而未获成功的平均生存期仅(34.3±25.5)天,差异具有统计学意义(P<0.05)。结论:TIPS应用于肝癌伴门脉癌栓的治疗可行,可改善生存质量、延长生存期,具有一定的临床应用价值。Objective： To investigate the value of transjugular intrahepatic portosystemic shunt （TIPS） in the treat ment of hepatocellular carcinoma （HCC） with portal vein tumor thrombosis （PVTT）. Methods：The clinical materials of patients having HCC with PVTT,which accepted the treatment of TIPS were recruited and retrospectively analyzed. In order to understand the improvement of main symptoms, complications and survival time. Results： Totally, thirteen patients of HCC with PVTT underwent TIPS, the operation was successfully performed in 10 patients. While 3 patients had upper gastrointestinal hemorrhage had the hemostasis successfully achieved,reduce of ascites were obtained in five of the seven pa tients. The average survival time were （112.1 ± 41.7）d in those patients had the operation successfully performed, whereas, which were only （34.3 ±25. 5）d in those patients had unsuccessful operation, showing statistically significant difference （P〈0.05）. Conclusion： TIPS is feasible in the treatment of HCC with PVTT,which could improve the quality of life,prolong the survival time, showing certain clinical practical value.

关 键 词：肝肿瘤 经颈静脉肝内门体分流术 门静脉癌栓 肝动脉门静脉瘘 

分 类 号：R735.7[医药卫生—肿瘤]