菌群、乙醇代谢与急性酒精中毒的关系研究  

The relationship between microbiota,ethanol metabolism and acute alcohol intoxication

作　　者：丁锐[1] 刘志洲[2] 庞立园 张瑾[1] 文姝[1] DING Rui LIU Zhizhou PANG Liyuan ZHANG Jin WEN Shu(Department of Microecology, Dalian Medical University, Dalian, Liaoning 116044, China)

机构地区：[1]大连医科大学微生态学教研室,辽宁大连116044 [2]解放军210医院403临床医学部,辽宁大连116021

出　　处：《中国微生态学杂志》2016年第11期1346-1348,共3页Chinese Journal of Microecology

基　　金：国家"863"计划(2014AA022209);国家自然科学基金(81370113)

摘　　要：酒是生活中常见的饮品,过度饮酒会对机体产生毒害作用。要防治急性酒精中毒首要的就是了解乙醇的代谢途径以及致病机制,从而找到加速乙醇代谢,减轻危害的方法。因为菌群与乙醇代谢相关,并可以通过菌群修复乙醇带来的损伤。本研究以乙醇代谢和损伤机制为基础,对菌群调节乙醇代谢及对酒精中毒的缓解作用进行综述。Alcohol is a common drink in life,excessive drinking will have a toxic effect on our bodies.To prevent acute alcohol intoxication,the first step is to understand the metabolic pathways of ethanol and pathogenic mechanism,so as to find a way to accelerate the ethanol metabolism,and reduce the harm.Because the bacteria is related to ethanol metabolism,they can alleviate the damage caused by ethanol via regulating microflora.On the basis of ethanol metabolism and damage mechanism,this paper reviewed the study on the effect of microflora in the regulation of ethanol metabolism and alleviation of alcohol intoxication.

关 键 词：乙醇代谢 肠道菌群 急性酒精中毒 

分 类 号：R378[医药卫生—病原生物学]