内镜下喷洒蛇毒血凝酶与金属钛夹治疗不明原因消化道出血的临床疗效比较  

Comparison of the Clinical Efficacy of Endoscopic Spray Snake Venom and Metal Titanium Clip in the Treatment of Obscure Gastrointestinal Bleeding

作　　者：王沁易 刘哲[2] 张煦[1] 张征[1] 李彦生[1] 

机构地区：[1]宝鸡市中医医院消化内科,陕西宝鸡721000 [2]延安大学附属医院心血管内科,陕西延安716000

出　　处：《现代生物医学进展》2016年第32期6309-6312,共4页Progress in Modern Biomedicine

基　　金：陕西省自然科学基金项目(1208085MC53)

摘　　要：目的:探讨内镜下喷洒蛇毒血凝酶与金属钛夹治疗不明原因消化道出血的临床疗效。方法:选取2013年8月至2015年12月本院收治的不明原因消化道出血患者82例,随机分为对照组和实验组,每组41例。对照组给予内镜下喷洒蛇毒血凝酶治疗,实验组给予金属钛夹止血治疗。观察两组患者经止血治疗后即时止血时间、外科手术率、输血量、症状消失时间和临床疗效、再出血率和出血量。结果:实验组即时止血率明显高于对照组,输血量低于对照组(P<0.05);实验组呕血消失时间、潜血转阴时间和引流液变清时间均小于对照组(P<0.05);实验组痊愈率、总有效率高于对照组(P<0.05);两组之间再出血率和出血量比较差异无统计学意义(P>0.05)。结论:金属钛夹较内镜下喷洒蛇毒血凝酶对不明原因消化道出血具有更好的临床疗效,且再出血率较低。Objective： To investigate the clinical efficacy of endoscopic spray snake venom and metal titanium clip in the treatment of obscure gastrointestinal bleeding. Methods： 82 patients with obscure gastrointestinal bleeding from August 2013 to December 2015 in our hospital were collected and randomly divided into the control group and the experimental group with 41 cases in each group. Patients in the control group were treated by endoscopic spray snake venom treatment; while patients in the experiment group were treated by metal titanium clip hemostatic treatment. The hemostatic instant hemostatic time, rate of surgery, blood transfusion amount, symptoms disappeared time and clinical efficacy were observed between two groups. Results： After treatment by the second solution, the instant hemostasis rate of experimental group was significant higher than that of the control group, the blood transfusion amount was lower than that of the control group（P 〈 0.05）; the hematemesis disappeared time, occult blood clearance time and drainage liquid cleared time of the experimental group were less than those of the control group（P 〈 0.05）; the cure rate and total effective rate of the experimental group were higher than those of the control group（P〈0.05）. No statistically significant difference was found in the bleeding rate and bleeding amount between two groups（P〉0.05）. Conclusion： Metal titanium clip had better clinical efficacy and lower bleeding rate than endoscopic spray snake venom in the treatment of obscure gastrointestinal bleeding.

关 键 词：蛇毒血凝酶 金属钛夹 即时止血率 临床疗效 再出血率 

分 类 号：R573.2[医药卫生—消化系统]