女性癌症患者生育力保存方法的研究综述  

Advances in fertility preservation in women with cancer

作　　者：马慜悦[1] 张士慧[1] 陆翀曌[1] 彭红梅[1] MA Minyue ZHANG Shihui LU Chongzhao PENG Hongmei(Chinese PLA General Hospital, Beijing 100853, China)

机构地区：[1]解放军总医院,北京100853

出　　处：《解放军医学院学报》2016年第11期1190-1192,1207,共4页Academic Journal of Chinese PLA Medical School

基　　金：国家自然科学基金青年基金(81300549)~~

摘　　要：罹患癌症的女性接受放疗和化疗会导致生育力下降。生殖医学与冷冻生物学的发展为这一群体的生育力保存提供了可能。通过卵巢皮质组织冷冻与移植、胚胎或卵母细胞冷冻、未成熟卵母细胞体外成熟、原始卵泡与窦前卵泡的体外培养等技术,女性癌症患者有机会延续生育力并产下子代,而干细胞在生育力保存中的作用仍处于研究阶段,尚未用于临床。Chemotherapy and radiotherapy may cause ovarian damage in women with cancer. Advances in reproductive medicine and cryobiology provide possibilities for fertility preservation in girls and young women with cancer, such as embryo cryopreservation or oocyte cryopreservation, in vitro maturation of immature oocyte, cryopreservation of ovarian tissue, primordial and preantral follicle culture and so on. Germ cells derived from stem cells are under research and still cannot be applicated clinically.

关 键 词：生育力保存 癌症 胚胎冷冻 卵巢组织冷冻 

分 类 号：R730.5[医药卫生—肿瘤]