同步放化疗对中晚期宫颈癌患者的效果分析  

Analysis of the Effect of Concurrent Radiotherapy and Chemotherapy on Patients with Advanced Cervical Cancer

作　　者：王晓静[1] 孟庆杰[1] 王振宏[1] 王海英[1] 王春英[1] 刘大伟[1] 张宝顺[1] Wang Xiao-jing Meng Qing-jie Wang Zhen-hong et al(Department of oncology, Fengrun District People＇s Hospital of Tangshan City, Tangshan 063000, Chin)

机构地区：[1]唐山市丰润区人民医院肿瘤科,唐山063000

出　　处：《中国医药导刊》2016年第11期1103-1104,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨同步放化疗对中晚期宫颈癌患者的治疗效果。方法:304例宫颈癌患者,随机平均分为单纯放疗组(D组)和同步放化疗组(T组),各152例,治疗结束对患者随访2年,观察两组治疗的有效性和毒副反应。结果:两组死亡患者为92例,D组55例,T组37例。Ⅱb期患者其死亡比低于Ⅲ期,无瘤生存比高于Ⅲ期,差异有统计学意义(P<0.05)。Ⅱb患者D组死亡比高于T组(P<0.05)。放化疗期间D组骨髓抑制的重度发生比和重度肠道反应的发生比均低于T组,差异有统计学意义(P<0.05)。结论:同步放化疗对中晚期宫颈癌患者效果好。Objective： To study the effect of concurrent radiotherapy and chemotherapy in the treatment of patients with advanced cervical cancer. Methods：304 cases of cervical cancer patients were randomly divided into radiotherapy alone group（Group D） and synchronous radiotherapy and chemotherapy group（Group T）, 152 cases each. At the end of treatment, patients were followed up for 2 years and observe the effectiveness and side effect of treatment in the two groups. Results： In the two groups, 92 patients died, 55 in the group D and 37 in the group T. In B phase II patients, the ratio of death to death was lower than that of stage III, and there was a significant difference（P〈0.05）. The death ratio of group D patients with B was higher than that in group T（P〈0.05）. During the period of chemotherapy, the incidence of severe intestinal reactions of group D was lower than that of group T, and the difference was statistically significant（P〈0.05）. Conclusion： Concurrent radiotherapy and chemotherapy is effective for patients with advanced cervical cancer.

关 键 词：宫颈癌 同步放化疗 恶性肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]