脑梗死患者脑灌注值与CISS亚型的关系  

Cerebral Infarction Patients' Perfusion Relationship with CISS Subtypes

作　　者：李晓满[1] 郑召龙 肖萌[1] 王莹莹 王泽颖[4] LI Xiao-man ZHENG Zhao-long XIAO Meng WANG Ying-ying WANG Ze-ying(Department of Neurology, Weifang Medical University, Weifang 261053, China Department of Imaging, Weifang Traditional Chinese Medicine Hospital Department of Neurology, Weifang Municipal Hospital Department of Eneephalopathy , Weifang Traditional Chinese Medicine Hospital)

机构地区：[1]潍坊医学院神经内科学教研室,山东潍坊261053 [2]潍坊市中医院影像科 [3]潍坊市市立医院神经内科 [4]潍坊市中医院脑病科

出　　处：《潍坊医学院学报》2016年第5期388-390,共3页Acta Academiae Medicinae Weifang

摘　　要：目的通过分析脑梗死患者脑灌注值,探讨脑灌注水平与中国缺血性卒中（CISS）亚型之间的关系,从而更好地指导临床治疗,减少脑卒中进展。方法连续选取6~72h内急性期脑梗死患者45例,入组患者40例,根据CISS分型标准分为穿支动脉疾病（PAD）组（n=10）、载体动脉阻塞穿支（CAP）组（n=18）、低灌注/栓子清除能力下降（LPERA）组（n=12）。测量40例入组患者两侧脑灌注值,分析与CISS亚型之间的关系。结果剔除其它各分型因资料不全5例患者,配对资料t检验分析脑两侧脑灌注值。40例入组患者两侧脑灌注值有统计学意义（P〈0.05）;LPERA组、CAP组两侧脑灌注值有统计学意义（P〈0.05）,且LPERA组两侧脑灌注差值[（19.02±13.58）ml·100g-1·min-1]大于CAP组[（5.69±8.68）ml·100g-1·min-1];PAD组两侧灌注值无统计学意义（P〉0.05）。结论急性脑梗死患者两侧脑血量存在差异,低灌注/栓子清除能力下降组两侧灌注值差别较大,其次为载体动脉阻塞穿支,穿支动脉疾病无意义。Objective To analyze the value of cerebral perfusion in patients with cerebral infarction, to ex- plore the relationship between cerebral perfusion and ischemic stroke（CISS） subtypes in China,to guide clinical treat- ment better, and to reduce the stroke progress. Methods Forty-five consecutive patients with acute cerebral infarction were selected from 6 to 72h,and 40 patients were enrolled in the group,according to the subtype of CISS classification standard for perforator artery disease group（ n = 10） ,carrier artery occlusion perforator group（ rt = 18} and low perfusion/ ability to remove emboli dropped group（n = 12）. To measure the cerebral perfusion values of the 40 patients with CISS, and to analyze the relationship between the subtypes of CISS. Results Paired t-test molecules between the two sides of the brain cerebral perfusion value ,40 cases in the group of patients with bilateral cerebral perfusion values were statisti- cally significant （ P 〈 0.05 ） ; LPERA group, group of cap on both sides of the perfusion values were statistically significant （ P 〈 0.05）, and LPERA groups [ （ 19.02 ± 13.58） ml ·100g-1· min- 1 ] on both sides of the brain perfusion difference was greater than CAP group [ （ 5.69± 8.68 ） ml ·100g-1· min -1 ] ; PAD groups on both sides of the perfusion values were no statistically significance （ P 〉 0.05 }. Conclusion Patients with acute cerebral infarction are different on both sides of the brain volume, hypoperfusion/impaired clearance of emboli groups on both sides of perfusion values vary greatly,followed by the cartier artery perforator,perforating artery occlusion without significance.

关 键 词：脑梗死 急性 动脉自旋标记灌注成像 CISS亚型 脑灌注值 

分 类 号：R743.3[医药卫生—神经病学与精神病学]