分化型甲状腺癌^(131)I治疗规范管理对患者生活质量的改善  

Standardized Management of Radioactive Iodine Therapy in Patients with Differentiated Thyroid Carcinoma

作　　者：符宇嘉 李诗运[1] 何燕[1] 吴虹燕[1] 卓小丽[1] 

机构地区：[1]海南省人民医院,海南海口570311

出　　处：《肿瘤学杂志》2016年第11期893-896,共4页Journal of Chinese Oncology

摘　　要：[目的]根据我院近20年分化型甲状腺癌(DTC)患者^(131)I治疗规范管理前、后的比较,总结其对患者生活质量的多方改善。[方法]将1996年1月至2005年12月规范管理前共治疗的DTC患者53人次与2006年1月至2015年12月规范管理后我科收住治疗DTC共869人次在各层面的生活质量方面进行对比分析。[结果]角色功能、认知功能、社会功能及总体健康状况规范管理后均有改善,差异有统计学意义(P<0.05),特别是情绪功能改善明显,评分有统计学差异(P<0.01),规范治疗后对失眠、疲倦、便秘等症状改善有意义,差异有统计学意义(P<0.05或P<0.01)。[结论]^(131)I治疗规范管理对DTC患者生活质量的改善有肯定意义。[Objective] To assess the standardized management of radioactive iodine therapy in patients with differentiated thyroid carcinoma. [Methods] Fifty three patients with differentiated thyroid carcinoma treated by radioactive iodine from Jan 1996 to Dec 2005（before standardized management） and 869 patients treated with radioactive iodine from Jan 2006 to Dec 2015（after standardized management） were included in the study. Quality of life was evaluated with EORTC QLQ-C30 scale and compared in two groups. [Results] The role function,cognitive function,social function,general health score,emotional function score in EORTC QLQ-C30 were significantly improved after standardized management（all P0.05）. The symptoms of insomnia,fatigue,constipation of after standardized management group were also improved（P 0.05）. [Conclusion]Standardized management of radioactive iodine therapy can significantly improve the quality of life in patients with differentiated thyroid carcinoma.

关 键 词：甲状腺肿瘤 131I 生活质量 

分 类 号：R736.1[医药卫生—肿瘤]