细胞衍生微粒与疾病  

Cell-derived Microparticles and Disease

作　　者：刘成海[1] 胡厚源[2] 

机构地区：[1]解放军第115医院心内科,西藏林芝市860000 [2]第三军医大学西南医院心内科,重庆市400038

出　　处：《中国动脉硬化杂志》2016年第11期1179-1182,共4页Chinese Journal of Arteriosclerosis

摘　　要：细胞衍生微粒产生于细胞激活或凋亡的过程中,来源包括血小板、内皮细胞、白细胞、红细胞等。它们不仅是介导细胞间传递多种生物活性物质的栽体,而且在许多疾病的发生、发展过程中扮演重要角色,如心血管疾病、感染性疾病、肿瘤和糖尿病等。本文主要从细胞衍生微粒的特性及其与疾病的关系作一综述。The cell-derived microparticles are produced in the process of cell activation or apoptosis,and the sources include platelets,endothelial cells,leukocytes,erythrocytes and so on. They not only are carrier mediated intercellular transfer of many kinds of bioactive substance,but also play an important role in the occurrence and development of many diseases,such as cardiovascular disease,infection disease,tumor and diabetes and so on. The characteristics of cell-derived microparticles and their relationship with the disease are reviewed in this paper.

关 键 词：细胞衍生微粒 生物活性 疾病 

分 类 号：R363[医药卫生—病理学]