早期降眼压治疗对高度近视LASIK术后屈光回退的影响  

Early effects in treatment of high myopia after LASIK refractive regression

作　　者：荣运久 宋雪玲 李璇 

机构地区：[1]解放军第八十九医院眼科,山东潍坊261021

出　　处：《中国实用眼科杂志》2016年第11期1178-1180,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨降眼压治疗在防治高度近视眼准分子激光角膜原位磨镶术后屈光回退中的作用。方法临床病例对照研究。选取2011年1月至2013年6月在解放军89医院眼科接受波前像差引导下的个体化切削的高度近视眼患者312例（604只眼），术前屈光度等效球镜在-6.15--11.25 D （-7.65±1.64）D。按手术时间顺序随机分成两组：研究组154例（296只眼），对照组158例（308只眼）。两组术后常规使用左氧氟沙星、氟米龙、玻璃酸钠滴眼液滴眼。研究组术后加点马来酸噻吗洛尔滴眼液，12 h 1次5周，每天1次4周。两组于术前、术后1个月、术后3个月进行眼压、验光及OrbscanⅡ检查并分析差异。结果术后1个月、3个月眼压指标，两组比较有统计学意义（P ≤0.05）；术后1个月、3个月角膜后表面前凸度（diff值）与术前差，两组比较有统计学意义（P ≤0.05）；术后1个月、3个月等效球镜屈光度，两组比较有统计学意义（P ≤0.05）。结论术后早期降眼压治疗能有效减轻高度近视眼准分子屈光手术后的角膜后表面前凸的程度，是防治术后屈光回退的有效方法。Objective To study the effects in treatment in the prevention and treatment of high myopia excimer laser corneal in-situ grinding with the role of postoperative refractive regression. Methods From January 2011 to Jtme 2011, 312 cases （604 eyes） with high myopia of preoperative dioptre equivalent spherical mirrors in-6.15--11.25D （-7.65±1.64D） accepted wavefront aberration guided by excimer laser. According to the operation time sequence those were divided into two groups at random： experimental group of 154 cases （296 eyes） and control group of 158 cases （308 eyes）. Levofloxacin and fluorine dragon, sodium hyaluronate eye drops were used routinely postoperative on both groups. Maleic acid thiamethoxam bisoprolol eye drops was added to experimental group 1 time every 12 hours for 5 weeks, 1 time a day for 4 weeks. Intraocular pressure, optometry and Orbscan II check were performed on two groups in preoperative and 1 month, 3 months postoperatively, and the differences were analyzed. Results Compared the two groups of postopera- tive intraocular pressure index on 1 month, 3 months showed statistical significance （P 〈0.05） or less. The two groups of corneal surface convex degree （diff） on 1 month and 3 months after sur- gery compared with preoperative had statistically significant （P 〈0.05） or less. The two groups of equivalent ball lens dioptre on after 1 month and 3 months compared with preoperative had statisti- cally significant （P 〈0.05） or less. Conclusions Early treatment of postoperative intraocular pressure can effectively alleviate cornea surface lordosis on high myopia after excimer refractive surgery, and is an effective method for prevention and treatment of postoperative refractive regression.

关 键 词：高度近视 眼压 屈光手术 

分 类 号：R776.1[医药卫生—眼科]