Comparative Genomic Analysis of Enterovirus 71 Revealed Six New Potential Neurovirulence-associated Sites  

作　　者：JIA Qing Jun CHEN Xin Yu LI De Zhou XU Juan Juan XU Zhi Gang DUAN Zhi Liang WEN Jin Sheng 

机构地区：[1]Institute of Arboviruses,School of Basic Medical Sciences,Wenzhou Medical University [2]Department of Clinical Laboratory,The Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University [3]Department of Liver,The Second Hospital of Ningbo

出　　处：《Biomedical and Environmental Sciences》2016年第10期767-772,共6页生物医学与环境科学（英文版）

基　　金：funded by Natural Science Foundation of Zhejiang(LQ14C010006);National Natural Science Foundation of China(81501363);Planned Science and Technology Project of Zhejiang(2014C33261)

摘　　要：In the present study,the complete genomes of four common（4/EV71/Wenzhou/CHN/2014,15/EV71/Wenzhou/CHN/2014,116/EV71/Wenzhou/CHN/2014,and 120/EV71/Wenzhou/CHN/2014）and two virulent（11/EV71/Wenzhou/CHN/2014and 109/EV71/Wenzhou/CHN/2014）enterovirus 71（EV71）isolates were sequenced and described.They are 7405 bp in length and belong to EV71 sub-genotype C4 （C4a cluster）.In the present study,the complete genomes of four common（4/EV71/Wenzhou/CHN/2014,15/EV71/Wenzhou/CHN/2014,116/EV71/Wenzhou/CHN/2014,and 120/EV71/Wenzhou/CHN/2014）and two virulent（11/EV71/Wenzhou/CHN/2014and 109/EV71/Wenzhou/CHN/2014）enterovirus 71（EV71）isolates were sequenced and described.They are 7405 bp in length and belong to EV71 sub-genotype C4 （C4a cluster）.

关 键 词：CHN UTR EV Comparative Genomic Analysis of Enterovirus 71 Revealed Six New Potential Neurovirulence-associated Sites 

分 类 号：R741[医药卫生—神经病学与精神病学]