盐酸法舒地尔配合双抗治疗短暂性脑缺血发作及对早期卒中的预防作用  

Curative Efficacy of Fasudil Hydrochloride Combined with Double Resistance in Treatment of Transient Ischemic Attack and Its Preventive Effect for Early Stoke

作　　者：代昌飞 张绒[1] 张维[1] 陈洁[1] 田慧娟[1] 王云龙[1] 

机构地区：[1]陕西省延安大学咸阳医院脑血管病科,陕西咸阳712000

出　　处：《现代生物医学进展》2016年第34期6772-6774,共3页Progress in Modern Biomedicine

摘　　要：目的:观察盐酸法舒地尔配合双抗(阿司匹林+氯吡格雷)治疗短暂性脑缺血发作(TIA)的临床疗效,并评价该治疗方案对早期卒中的预防作用。方法:将310例TIA患者随机分为2组,对照组(n=155)给予双抗治疗,观察组(n=155)在对照组基础上加用盐酸法舒地尔。比较2组患者治疗前后的临床疗效以及ABCD2评分。结果:观察组的临床总有效率高于对照组(P<0.05);观察组的高危人群明显少于对照组,低危人群明显多于对照组(P<0.05)。结论:盐酸法舒地尔配合双抗治疗短暂性脑缺血发作的临床效果明显优于单纯双抗治疗,对早期卒中的预防作用也更加明显。Objective： To observe the clinical efficacy of Fasudil Hydrochloride combined with double resistance in treatment for transient ischemic attack （TIA） and its preventive effect for early stoke. Methods： 310 cases with TIA were randomly divided into 2 groups, and the patients in control group were given double resistance treatment, and the patients in observation group were given Fasudil Hydrochloride on the base of control group. The clinical efficacy and ABCD2 score of two groups before and after treatment were compared. Results： The total clinical efficacy of observation group was higher than that of control group（P〈0.05）; the high-risk group in the observation were less than the control group, the low-risk group were more than the control group e （P〈0.05）. Conclusions： Fasudil Hydrochloride combined with double resistance is superior to double resistance in treatment of TIA and has obvious prevention effect on the early stroke.

关 键 词：短暂性脑缺血发作 盐酸法舒地尔 阿司匹林 氯吡格雷 早期卒中 

分 类 号：R743[医药卫生—神经病学与精神病学]