推拿手法联合跑台训练促进大鼠坐骨神经再生的效果  

Effects of Tuina Combined with Treadmill Training on Regeneration of Sciatic Nerve in Rats

作　　者：马书杰[1,2] 严隽陶[1] 陶然[2] 陆永嘉[1] 王春红[1] 潘俊峰[1] 马颖[1] 周帆[1] 鲍嘉敏 符利娟[2] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院推拿科,上海市200437 [2]上海中医药大学康复医学院,上海市201203

出　　处：《中国康复理论与实践》2016年第11期1276-1280,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家自然科学基金面上项目(No.30973806;No.81373764);国家自然科学基金青年基金项目(No.81603713)

摘　　要：目的探讨推拿手法联合跑台训练对坐骨神经横断伤外膜修复后促进神经再生的效应及途径。方法 96只Sprague-Dawley大鼠随机分为正常对照组、缝合对照组和缝合手法组,每组32只。后两组建立坐骨神经横断伤外膜缝合模型,缝合手法组给予捻揉手法及跑台训练,每天1次。分别于干预后2、3、4、8周各组取8只大鼠检测坐骨神经传导速度、再生神经轴突数及施万细胞数。结果与缝合对照组比较,缝合手法组坐骨神经传导速度在干预后4周、8周加快(P<0.05),轴突数目在2周、4周时有显著性差异(P<0.05);施万细胞数无显著性差异(P>0.05)。结论推拿手法联合跑台训练可促进损伤的周围神经再生。Objective To explore the effect of Tuina combined with treadmill training on nerve regeneration after sciatic nerve transection. Methods Ninty-six Sprague-Dawley rats were randomly divided into normal group（n=32）, model group（n=32） and treatment group（n=32）. The sciatic nerve was transected and the epineurium was sutured in the latter two groups. The treatment group was given Tuina manipulation and treadmill training once a day. Eight rats from each group were detected their sciatic nerve conduction velocity（NCV）, the number of axons and Schwann cells（SCs） two, three, four and eight weeks after intervention. Results Compared with the model group, the NCV accelerated in the treatment group four and eight weeks after intervention（P〈0.05）; while the number of axons was significantly different two and four weeks after intervention（P〈0.05）, and the number of SCs was not very different between the treatment group and the model group after intervention（P〉0.05）. Conclusion Tuina combined with treadmill training may promote the regeneration of peripheral nerve after injury in rats.

关 键 词：推拿 跑台 神经再生 坐骨神经 传导速度 大鼠 

分 类 号：R745.4[医药卫生—神经病学与精神病学]