武汉某医院门诊患者对药物临床试验知晓度分析  

Analysis on the Public Awareness of Drug Clinical Trials in Outpatients

作　　者：徐宜咏[1] 曹羽明 李斐[1] 詹余平 张元珍[1] 

机构地区：[1]武汉大学中南医院妇产科,湖北武汉430071

出　　处：《武汉大学学报（医学版）》2016年第6期1023-1026,1034,共5页Medical Journal of Wuhan University

基　　金：湖北省重大科技创新计划资助项目(编号:2013ACA006)

摘　　要：目的:了解妇产科门诊患者对药物临床试验的知晓度,为开展药物临床试验相关知识培训工作提供依据。方法:自行设计调查问卷,选择某医院妇产科门诊患者及家属进行问卷调查。结果:发放问卷158份,回收有效问卷145份。17.93%调查对象表示没有听说过药物临床试验。48.28%调查对象对药物临床试验及相关知识知晓合格。仅3.37%调查对象对药物临床试验中受试者享有权益知晓,86.50%表示没有听说过药物临床试验中伦理委员会及其职能。性别、文化程度及医疗支出对调查对象知晓合格程度有影响,文化程度对知晓是否合格影响最大(OR:2.312,95%CI:1.061-2.148)。结论:调查对象对药物临床试验基本认知不足,建议针对性加强药物临床试验相关知识宣传,增强公众认识。Objective：To investigate the public awareness of drug clinical trials and the related problems,and further to provide reference to the training programme of the drug clinical trials.Methods：A field survey on outpatients in our hospital was performed using aquestionnaire designed by ourselves.Results：In the 158 questionnaires we sent out,145 valid questionnaires were collected,and among which 17.93% of the respondents described they had never heard of drug clinical trials.The awareness rate of the drug clinical trials was 48.28%.Only 3.37%of the respondents knew about the rights and interests of subjects in drug clinical trials and 86.50% of the respondents had never heard of the ethics committee and its functions.Gender,educational level and medical expenditure were related to the objects in the survey.The largest factor of the score is the education level（OR：2.312,95%CI：1.061-2.148）.Conclusion：The respondents＇ cognition of the drug clinical trial was not sufficient.We suggest stepping up the publicity of the knowledge of drug clinical trials to raise public awareness.

关 键 词：药物临床试验 调查问卷 知晓度 

分 类 号：R969.4[医药卫生—药理学]