miRNA-204与肿瘤关系的研究进展  

Research Progress of the Relationship between miRNA-204 and Cancers

作　　者：江海波[1] 葛瑞祥 钱冬喜 毛捷[1] 

机构地区：[1]皖南医学院弋矶山医院神经外科,安徽芜湖241001

出　　处：《沈阳医学院学报》2016年第6期479-482,共4页Journal of Shenyang Medical College

基　　金：安徽省高校自然科学研究项目(No.KJ2015A141)

摘　　要：miRNA-204在人体中广泛表达,并在很多肿瘤中表达异常。miRNA-204在人体内通过对靶基因的调节,在肿瘤的发生发展过程中起重要作用。miRNA-204常作为肿瘤的抑癌基因,且通过相关分子机制可以抑制肿瘤的侵袭、转移,也可以作为潜在的分子标记物用于肿瘤的治疗。对miRNA-204的深入研究,可对肿瘤的预防及治疗提供新思路。miRNA-204 is widely expressed in human body and also aberrantly expressed in almost all human cancers. It is proved that miRNA-204 plays an important role in the occurrence and development of cancers through regulating its target genes in human body. miRNA-204 is often used as a tumor suppressor to inhibit tumor invasion and metastasis through the related molecular mechanism. Meanwhile,miRNA-204 can also be used as potential molecular marker in the treatment of cancers. With a deeper study of miRNA-204,it is possible to provide new ideas for the prevention and treatment of cancers.

关 键 词：miRNA-204 肿瘤 靶基因 

分 类 号：R730.2[医药卫生—肿瘤]