急性脑梗死患者简易胰岛素抵抗指数水平的临床研究  

Clinical study on simple insulin resistance index in patients with acute cerebral infarction

作　　者：秦晓凌[1] 田永芳[1] 辛在娥[1] 赵莉[1] 

机构地区：[1]江苏徐州市中心医院神经内科,徐州221000

出　　处：《中国实用神经疾病杂志》2016年第24期32-33,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的观察急性脑梗死患者的甘油三酯血糖指数(简易胰岛素抵抗指数TyG)和稳态模型评估的胰岛素抵抗指数(HOMA-IR)特点,并分析两指数的相关性。方法采用放射免疫法测定46例急性脑梗死(ACI)及40例健康对照者的空腹血胰岛素、空腹血糖、TG水平,计算简易胰岛素抵抗指数(TyG)和稳态模型评估法胰岛素抵抗指数(HOMA-IR)。结果急性脑梗死组TyG和HOMA-IR均较对照组增高(P<0.05);急性脑梗死组和对照组TyG和HOMA-IR具有良好的相关性(分别为r=0.34,P<0.05;r=0.27,P<0.05)。结论急性脑梗死患者存在胰岛素抵抗,TyG评价胰岛素抵抗是一种简单准确的方法。Objective To observe the characteristics of triglyceride-blood glucose index （simple insulin resistance index, TyG） and homeostasis model assessment of insulin resistance （HOMA-IR） in patients with acute cerebral infarction （ACI）, and analyze the correlation. Methods The levels of fasting blood insulin,fasting blood glucose （FBG） and triglycerides （TG） from 46 ACI patients and 40 healthy controls were measured by radio-immunoassay to calculate TyG and HOMA-IR. Results Both TyG and HOMA-IR were higher in ACI group than those in control group （P〈0.05） ;TyG had a good correlation with HOMA-IR in both two groups （r=0.34,P〈0.05;r=0.27,P〈0.05）. Conclusion Insulin resistance exists in acute cerebral infarction and TyG may be a simple and accurate method to evaluate insulin resistance.

关 键 词：急性脑梗死 胰岛素抵抗 甘油三酯血糖指数 

分 类 号：R743.33[医药卫生—神经病学与精神病学]