颅内动脉瘤破裂患者生存状况的相关因素研究  

Related affecting factors on survival status in patients with ruptured intracranial aneurysm

作　　者：陈宏尊[1] 庞元龙[2] 

机构地区：[1]解放军第425医院神经外科,三亚572008 [2]解放军第425医院外科,三亚572008

出　　处：《中国实用神经疾病杂志》2016年第22期3-4,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨颅内动脉瘤破裂患者生存状况的相关因素。方法选取2011-01-2015-01在我院接受治疗的颅内动脉瘤破裂患者200例,采用回顾性分析对患者的年龄、收入状况、有无负面情绪、有无头痛、Hunt-Hess分级、手术方式、手术时机等一般资料进行单因素分析,然后对颅内动脉瘤破裂患者生存状况可能造成影响的多种因素进行Logistic回归分析,采用GOS评分作为患者的生存状况的评价方法。结果单因素分析示,患者的收入状况（χ~2=2.717,P=0.094）、有无负面情绪（χ~2=3.175,P=0.063）并不是对颅内动脉瘤破裂患者生存状况造成影响的因素,差异无统计学意义（P〉0.05）;而患者的年龄（χ~2=4.015,P=0.043）、头痛情况（χ~2=13.641,P=0.000）、Hunt-Hess分级（χ~2=16.347,P=0.000）、手术方式（χ~2=5.031,P=0.023）及手术时机（χ~2=6.634,P=0.010）是对颅内动脉瘤破裂患者生存状况造成影响的因素,差异具有统计学意义（P〈0.05）。对颅内动脉瘤破裂患者生存状况可能造成影响的各种因素进行多种因素Logistic回归分析发现,患者的年龄、Hunt-Hess分级、手术方式、手术时机是影响颅内动脉瘤破裂患者生存状况的独立因素（P〈0.05）;患者的头痛状况不是影响颅内动脉瘤破裂患者生存状况的独立因素（P〉0.05）。结论患者的年龄、Hunt-Hess分级、手术方式、手术时机是影响颅内动脉瘤破裂患者生存状况的关键。Objective To explore related factors on survival status in patients with ruptured intracranial aneurysm.Method All of 200 cases with ruptured intracranial aneurysm were chosen in our hospital from January 2011 to January 2015.Then we performed this retrospective analysis on clinical data including age,income status,negative emotions,headache,HuntHess classification,operation way,operation opportunity and so on.The related factors of survival status observed from univariate analysis were further calculated by Logistic regression analysis.And GOS scores were applied to evaluate survival status.Results Univariate analysis showed that although neither income status（χ2=2.717,P=0.094）nor negative emotions（χ2=3.175,P=0.063）were the influencing factors on survival status（P〈0.05）,the patients＇ age（χ2=4.015,P=0.043）,headache（χ2=13.641,P=0.000）,Hunt-Hess grade（χ2=16.347,P=0.000）,surgical approach（χ2=5.031,P=0.023）and operation opportunity（χ2=6.634,P=0.010）were the affecting factors（P〈0.05）.Further Logistic regression analysis revealed that age,Hunt-Hess grade,surgical approach and operation opportunity except headache were the independent factors（P〈0.05）.Conclusion Patients＇ age,Hunt-Hess classification,operation method and operation opportunity may be the key to survival status in patients with ruptured intracranial aneurysms.

关 键 词：颅内动脉瘤 生存状况 相关因素 

分 类 号：R739.4[医药卫生—肿瘤]