GC-MS联用法分析白芷挥发油的化学成分  

Analysis of the volatile components of angelica dahurica by GC-MS

作　　者：高岩[1] 王知斌[1] 杨春娟[1] 吴高松[1] 陈亚军[1] 匡海学[1] 

机构地区：[1]黑龙江中医药大学,教育部北药基础与应用研究重点实验室,黑龙江省中药天然药物药效物质基础研究重点实验室,黑龙江哈尔滨150040

出　　处：《化学工程师》2016年第11期20-22,共3页Chemical Engineer

基　　金：教育部博士点基金项(20132327120002);黑龙江中医药大学“优秀创新人才”支持项目(2012RCD05);黑龙江中医药大学“杰出人才培养”基金项目(2012cj02)

摘　　要：目的:研究白芷挥发油的化学成分,并推测其主要成分的质谱裂解规律。方法:采用水蒸汽蒸馏法提取白芷挥发油,GC毛细管柱色谱法分析并以峰面积归一化法检测化学成分的相对含量,再以气相色谱-质谱联用技术辅助人工检索鉴定其化学成分。结果:鉴定出39个化合物并推测单萜及其衍生物的质谱裂解规律为支链断裂后六元环开环。结论:本研究通过对白芷挥发油成分的分析及其主成分化合物质谱裂解规律的总结,为其质量控制及标准制定提供科学依据。Objective：To analyze the constituents of the essential oil from Angelica dahurica, and to speculate the mass frag-mentation rules of its main components .Method： The essential oil was extracted by water-steam dis- tillation and analyzed by GC-MS,relative content of compositions for calculating with peak area normalization method.The components were determined with nor-malization method,and identified by GC-MS and co-artificial searches.Result：Thirty-nine components were identified.The mass frag-mentation rules of monoterpene and its derivatives were side-chain cleavage then ring-opening.Conclusion：This study provided scientific foundation for the quality control and standard establishment of A. dahurica by analyzing its essential oil components and speculating the mass frag-mentation rules of monoterpene and its derivatives.

关 键 词：白芷 挥发油 气相色谱-质谱 

分 类 号：R284[医药卫生—中药学]