HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea  

作　　者：Yoshiki Koriyama Ayako Furukawa 

机构地区：[1]Graduate School and Faculty of Pharmaceutical Sciences,Suzuka University of Medical Science

出　　处：《Neural Regeneration Research》2016年第11期1758-1759,共2页中国神经再生研究（英文版）

摘　　要：Retinal degenerative diseases （RDs） such as retinitis pigmentosa （RP） are characterized by slowly progressive photoreceptor cell death, but the molecular mechanism underlying RP remains unclear. Animal models for RP have led to a better understand- ing of the disease pathological mechanisms, yet it remains difficult to identify an appropriate genetic model for RDs in general because there are many causative genes （Rossmiller et al., 2012）.Retinal degenerative diseases （RDs） such as retinitis pigmentosa （RP） are characterized by slowly progressive photoreceptor cell death, but the molecular mechanism underlying RP remains unclear. Animal models for RP have led to a better understand- ing of the disease pathological mechanisms, yet it remains difficult to identify an appropriate genetic model for RDs in general because there are many causative genes （Rossmiller et al., 2012）.

关 键 词：HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea cell MNU 

分 类 号：R774.1[医药卫生—眼科]