常压氧联合高压氧治疗老年高血压性脑梗死患者神经功能缺损及血液流变学的改变  

Atmospheric oxygen coupled with hyperbaric oxygen in the treatment of neurologic impairment with hemorheology in senile patients following hypertensive cerebral infarction

作　　者：方根强[1] 王根发[1] 

机构地区：[1]上海交通大学医学院附属新华医院老年医学科,上海200092

出　　处：《中华航海医学与高气压医学杂志》2016年第5期378-381,共4页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的 探讨常压氧联合高压氧治疗老年高血压性脑梗死患者神经功能缺损临床疗效及血液流变学的变化.方法 选取于本院诊治的93例老年高血压性脑梗死患者作为研究对象,按照治疗方法分为2组,观察组48例采用常压氧联合高压氧治疗,对照组45例仅采用高压氧治疗,观察2组患者神经功能缺损临床疗效的差异及血液流变学的改变.结果 观察组临床治疗总有效率（97.9％）显著高于对照组（82.2％）,差异有统计学意义（P＜0.05）;治疗前2组神经功能缺损程度评分、Barthel评分差异均无统计学意义（P＞0.05）,治疗后观察组神经功能缺损程度评分及Barthel评分[（7.4±4.1）分,（56.3±15.2）分]改善均显著优于对照组[（11.2±5.4）分,（43.3±10.7）分],差异均有统计学意义（P＜0.05）;治疗后观察组各项动态血压参数、血液流变学指标变化均明显优于对照组,差异有统计学意义（P＜0.05）.结论 老年高血压性脑梗死患者采用常压氧联合高压氧治疗疗效更显著,具有促进患者神经功能恢复及改善生活质量等积极意义.Objective To investigate the clinical efficacy of atmospheric oxygen coupled with hyperbaric oxygen （HBO） in the treatment of neurologic impairment with hemorheology in senile patients following hypertensive cerebral infarction.Methods Ninety-three senile patients with hypertensive cerebral infarction treated in our hospital were recruited as research subjects,and were divided into the observation group （48 cases） and the control group （45 cases） in accordance with different treatment methods.The observation group was treated with atmospheric oxygen couple with hyperbaric oxygen therapy,while the control group was only given HBO therapy.Then,differences in the clinical efficacy and changes in hemorheology were closely observed and compared between the 2 groups.Results Total efficacy of the observation group （97.9%） was significantly higher than that of the control group （82.2%）,and statistical significance could be noted,when comparisons were made between them （P 〈 0.05）.There was no statistical significance in neurological deficit scores and Barthel scores for the 2 groups before treatment （P 〉 0.05）.However,those scores of the observation group after treatment [（7.4 ±4.1）,（56.3 ± 15.2）] were significantly superior to those of the control group [（11.2 ± 5.4）,（43.3 ± 10.7）],and statistical significance could be seen when comparisons were made between them（P 〈 0.05）.Following treatment,the parameters of blood pressure and changes in hemorheology of the observation group were significantly superior to those of the control group,with statistical significance （P 〈 0.05）.Conclusions In the treatment of neurologic impairment with hemorheology of senile patients,atmospheric oxygen coupled with HBO could achieve better clinical efficacy,and this treatment regimen was of positive significance for the recovery of neural function and improvement of life quality of the patients.

关 键 词：老年 高血压 脑梗死 常压氧 高压氧 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R544.1[医药卫生—临床医学]