原发性面肌痉挛患者病情与心理状态的相关性分析  

Analysis of association between the condition and psychological state of patients with primary hemifacial spasm

作　　者：朱浩然[1] 张宁[1] 李馨歆 陆玉玲[1] 

机构地区：[1]中南大学湘雅医院,湖南省长沙市410008

出　　处：《国际神经病学神经外科学杂志》2016年第5期418-421,共4页Journal of International Neurology and Neurosurgery

摘　　要：目的评估原发性面肌痉挛(HFS)患者焦虑、抑郁状态,探讨病情与心理状态相关性。方法对2013年至2015年就诊于中南大学湘雅医院肌张力障碍专科治疗门诊的120例原发性面肌痉挛患者进行临床资料收集,焦虑自评量表(SAS)及抑郁自评量表(SDS)调查并通过SPSS17.0统计软件统计分析相关性。结果女性患者中平均SAS标准分、平均SDS标准分均大于男性患者,差异无统计学意义(P>0.05);11.4%的女性患者存在焦虑症状,15.4%的女性患者存在抑郁症状,两者均明显高于男性患者,但差异无统计学意义(P>0.05)。病程10年及以上的患者平均SAS/SDS标准分高于病程10年以下的患者,差异有统计学意义(P<0.05)。痉挛强度为重度的患者平均SAS/SDS标准分高于痉挛强度为轻中度的患者,差异有统计学意义(P<0.05)。痉挛程度为重度的患者平均SAS/SDS标准分高于痉挛程度为轻中度的患者,差异有统计学意义(P<0.05)。经Logistic多因素回归分析,面肌痉挛患者的病程长短、痉挛强度以及痉挛程度为面肌痉挛患者伴发焦虑抑郁情绪的危险因素。结论原发性面肌痉挛患者更易产生焦虑、抑郁情绪。原发性面肌痉挛患者的焦虑抑郁情绪与性别无关,与病程长短、痉挛强度、痉挛程度呈现一定正相关性。Objective To evaluate the anxiety or depression of patients with primary hemifacial spasm （HFS） and to explore the association between the disease state and psychological condition of patients with HFS. Methods The clinical data of 120 HFS patients, who visited the Botulinum Clinic of Xiangya Hospital of Central South University between 2013 and 2015, were collected in this study. The Self-Rating Anxiety Scale （SAS） and Self-Rating Depression Scale （SDS） were used to test all patients. Statistical analysis was performed using SPSS version 17.0 for the association. Results Our results showed that the mean SAS and SDS standard scores of fe- male patients were higher than those of the male patients, although the differences were not statistically significant （P 〉 0.05）. Of all female patients, 11.4% suffered from anxiety, and 15.4% suffered from depression; these were more prevalent in female patients than in male patients, but the differences between the two gender groups were not significant （P 〉 0. 05）. Additionally, the mean SAS and SDS standard scores were significantly higher in HFS patients with a duration of 10 years or longer than in those with a duration shorter than 10 years （P 〈 0.05）. Patients with high intensity and degree of spasm had significantly higher SAS and SDS standard scores than those with medium or low intensity and degree of spasm （P 〈 0.05 ）. The logistic multivariate regression analyses confirmed that the length of HFS duration and the intensity and degree of spasm were risk factors for anxiety and depression in HFS patients. Conclusions Compared with healthy people, HFS patients are more likely to experience anxiety and depression, which are positively associated with the duration of disease and the intensity and degree of spasm, but are not associated with gender.

关 键 词：原发性面肌痉挛 焦虑 抑郁 

分 类 号：R745.12[医药卫生—神经病学与精神病学]