阿奇霉素在急性肠炎治疗中的应用价值  

The Application Value of Azithromycin in the Treatment of Acute Enteritis

作　　者：于涛[1] 

机构地区：[1]通辽市医院消化内科,内蒙古通辽028000

出　　处：《中国继续医学教育》2016年第33期157-158,共2页China Continuing Medical Education

摘　　要：目的探讨分析阿奇霉素在急性肠炎治疗中的应用价值。方法本研究选取2014年10月~2016年2月我院收治的120例急性肠炎患者作为研究对象,随机分为观察组和对照组,各60例,所有患者均给予解除胃肠痉挛、止吐、维持水电解质平衡等基础治疗;在此基础上,对照组给予左氧氟沙星治疗;观察组给予阿奇霉素治疗;均连续治疗3 d,对比分析两组疗效。结果经治疗后观察组患者退烧时间及止泻时间均低于对照组（P均〈0.05）;观察组患者治疗总有效率高于对照组（93.3%vs.78.3%,P〈0.05）;治疗过程中两组均未出现严重并发症,观察组出现2例恶心,1例呕吐,不良反应发生率为5%;对照组出现2例恶心,不良反应发生率为3.3%;两组比较差异无统计学意义（P〉0.05）。结论阿奇霉素用于治疗急性肠炎的治疗,可显著缩短止泻退烧时间并提高治疗疗效,同时不会增加不良反应的发生。Objective To explore the application value of azithromycin in the treatment of acute enteritis. Methods 120 cases of acute enteritis from October 2014 to February 2016 were selected and divided into observation group and control group, 60 cases in each group. All the cases were accepted basic treatment as alleviated stomach bowel, antiemetic, kept water electrolyte balance. And on this basis, the cases in control group were taken levofloxacin and observation group were taken azithromycin for 3 days. The clinical effect was compared. Results After treatment, the body temperature recovery time and diarrhea relieving time in observation group was lower than control group, the difference was statistically significant（P〈0.05）. The effective rate in observation group was higher than control group, the difference was statistically significant（93.3% vs. 78.3%, P〈0.05）. There was no serious complications occurred in the two groups. In observation group, there was 2 cases occurred nausea and 1 case of emesis. The incidence of adverse reactions was 5%. In control group, there was 2 cases occurred nausea. The incidence of adverse reactions was 3.3%. It had no differences between the two groups（P〉0.05）. Conclusion Azithromycin in the treatment of acute enteritis can shorten the body temperature recovery time and diarrhea relieving time without an incremental advance. It should be extended in clinic.

关 键 词：急性肠炎 阿奇霉素 左氧氟沙星 

分 类 号：R574[医药卫生—消化系统]