三种药物联合治疗肠易激综合征的应用价值  

The Application Value of Three Kinds of Drugs in the Treatment of Irritable Bowel Syndrome

作　　者：王菲[1] 

机构地区：[1]吉林医药学院附属医院消化二科,吉林吉林132000

出　　处：《中国继续医学教育》2016年第32期166-168,共3页China Continuing Medical Education

摘　　要：目的 探讨枯草杆菌二联活菌、马来酸曲美布汀联合氟西汀治疗肠易激综合征的临床价值。方法 选择2014年1月-2016年1月我院接受治疗的肠易激综合征患者96例,随机分成治疗组（n=48）和对照组（n=48）,给予对照组患者服用枯草杆菌二联活菌治疗,观察组在对照组的基础上加用马来酸曲美布汀、氟西汀治疗,治疗后判定临床疗效。结果 观察组患者治疗总有效率（93.7%）高于对照组（79.17%）,差异有统计学意义（P〈0.05）。结论 肠易激综合征应用枯草杆菌二联活菌、马来酸曲美布汀联合氟西汀疗效确切,安全性高。Objective To investigate the clinical value of l the treatment for irritable bowel syndrome by the combination with live binary bacillus subtilis and trimebutine maleate.Methods 96 cases of patients with irritable bowel syndrome treated in our hospital from January 2014 to January 2016 were randomly divided into treatment group （n=48） and control group （n=48）. Patients in the control group were treated with Bacillus subtilis two live bacteria. The control group was used maleic acid trimebutine, lfuoxetine treatment on the basis of treatment of the observation group. To determine the clinical effcacy of all patients after the treatment.Results The total effective rate of the observation group after treatment （93.7%） was signiifcantly higher than that in the control group （79.17%）, and the difference was statistically signiifcant （P 〈 0.05）. ConclusionThe curative effect of the treatment with high safety for irritable bowel syndrome by the combination with bacillus subtilis duplex living bacterium and trimebutine maleate is excellent.

关 键 词：枯草杆菌二联活菌 马来酸曲美布汀 氟西汀 肠易激综合征 临床价值 

分 类 号：R574.3[医药卫生—消化系统]