CT灌注扫描对小肝癌分化及肝硬化程度的判断价值  

Value of CT perfusion scan in judging differentiation of small liver cancer and degree of liver cirrhosis

作　　者：曾金光[1] 

机构地区：[1]成都医学院第一附属医院放射科,四川成都610500

出　　处：《临床和实验医学杂志》2016年第23期2365-2367,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨CT灌注扫描对小肝癌分化及肝硬化程度的判断价值。方法纳入2012年6月至2015年12月收治小肝癌患者47例作为观察组,同期行健康检查的健康志愿者47名作为对照组。均行肝脏CT多期动态增强扫描及灌注扫描。记录并比较两组肝动脉分数(HAF)、平均通过时间(MTT)、血容量(BV)、血流量(BF)、表面通透性(PS)等灌注参数。结果小肝癌CT表现以稍低密度结节影、边界不清、不均匀强化为主。不同肝硬化程度小肝癌与对照组之间HAF、HAP的差异均有统计学意义(P<0.05),且随着肝硬化程度加重,HAF及HAP相应增大;不同分级小肝癌患者与对照组之间HAF、HAP、PS的差异均有统计学意义(P<0.05),且随着肝硬化分化程度增加,HAF及HAP相应增大。结论肝脏CT灌注扫描可有效评估小肝癌患者分化程度及肝硬化程度,利于患者病情的判断。Objective To explore the value of CT perfusion scan in judging differentiation of small liver cancer and degree of liver cirrhosis. Methods 47 patients with small liver cancer who were treated in our hospital from June 2012 to December 2015 were included in the observation group. 47 healthy volunteers who underwent health examination in the same period were included in the control group. All the subjects underwent hepatic muti- phase dynamic contrast- enhanced CT scan and perfusion scan. Perfusion parameters such as HAF,MTT,BV,BF and PS were compared between the two groups. Results CT findings of small liver cancer mainly included slightly lower density nodular shadow,unclear boundaries and inhomogeneous enhancement. The differences in HAF and HAP between different degrees of liver cirrhosis in small liver cancer and the control group were statistically significant（ P〈0. 05）. The differences in HAF,HAP and PS between patients with different grades of small liver cancer and the control group were statistically significant（ P〈0. 05）. Conclusion Hepatic CT perfusion scanning can effectively be used to evaluate the degree of differentiation of small liver cancer and liver cirrhosis,which is conductive to determine the condition of patients.

关 键 词：小肝癌 肝硬化 CT灌注扫描 分化 分级 

分 类 号：R735.7[医药卫生—肿瘤] R575.2[医药卫生—临床医学] R730.44