De novo癌2例报道  

Reports of two de novo cancer cases

作　　者：马剑娟 胡雯[1] 晁园[1] 吾红光 潘文胜[3] Ma Jianjuan Hu Wen Chao Yuan et al(Department of Gastroenterology, Binjiang Branch, The Second Affiliated Hospital of Zhejiang University Medical School, Hangzhou, 310000, China)

机构地区：[1]浙江大学医学院附属第二医院滨江院区消化内科,浙江杭州310000 [2]衢州市第二人民医院消化内科,浙江衢州324000 [3]浙江大学医学院附属第二医院消化内科,浙江杭州310009

出　　处：《实用肿瘤杂志》2016年第6期555-557,共3页Journal of Practical Oncology

基　　金：国家自然科学基金(81372302);国家公益卫生行业专项基金(200802112);浙江省自然科学基金(Y12H160121;LY13H200001);浙江省科技厅重大科技专项(2013C03044-5);浙江省卫生厅一般项目(201343550;2016KYB333);浙江省教育厅一般项目(Y201328489)

摘　　要：本文介绍2例de novo癌病例诊治过程。2例患者肠镜检查时原发病灶为扁平样隆起,易被忽视;分别予内镜下黏膜切除术(endoscopic mucosa resection,EMR)术和内镜下黏膜剥离术(endoscopic submucosal dissection,ESD),术后病理均提示中分化腺癌,需进一步追加手术。2例现病情稳定,生活质量良好。肠镜下早期发现de novo癌尤为重要,如不能确诊,密切观察病变变化,可提高de novo癌的早期诊治率,对争取治疗时机、改变预后有决定性作用。The diagnosis and treatment of two de novo cancer patients was described in this report. The primary lesions of these two patients were slightly elevated under colonoscopy,which were easily ignored. The patients were treated with endoscopic mucosa resection（ EMR） and endoscopic submucosal dissection（ ESD） respectively. In both cases,the pathology diagnoses were moderately differentiated adenocarcinoma,and both patients needed further surgical procedures.The disease status of the two patients are stable and the life quality is well. The diagnosis and treatment process of these cases indicated that early diagnosis under endoscopy is critical for de novo cancer. If a definite diagnosis cannot be made,close endoscopic follow-up is important for the early diagnosis of de novo cancer which plays a pivotal role in determining the optimal time for surgery and improving prognosis.

关 键 词：结肠肿瘤 直肠肿瘤 内窥镜 

分 类 号：R735.3[医药卫生—肿瘤]