胰腺导管内乳头状黏液性肿瘤的病理学及预后分析  

Pathological and prognostic analysis of pancreatic ductal papillary mucinous tumors

作　　者：刘晓辉[1] 

机构地区：[1]赤峰学院医学院,024000

出　　处：《国际医药卫生导报》2016年第23期3579-3581,共3页International Medicine and Health Guidance News

摘　　要：目的研究胰腺导管内乳头状黏液性肿瘤的病理学并进行预后分析。方法回顾性分析2009年2月至2011年1月于本院附属医院接受手术切除的胰腺导管内乳头状黏液性肿瘤患者93例，其中浸润性癌患者51例、非浸润性癌患者42例。对所有患者病历资料进行统计，并对两组患者病理特征及手术效果进行分析。结果浸润性组消瘦、CA199〉37U／ml以及皮肤巩膜黄染发生率均显著高于非浸润性组。浸润性组复发率为41．18％（21／51），显著高于非浸润性组的7．14％（3／42）；而5年生存率为56．86％（29／51），明显低于非浸润性组的97．62％（41／42），差异均有统计学意义（P〈0．05）。结论经手术治疗后非浸润性胰腺导管内乳头状黏液性肿瘤患者预后较好，尽早进行手术治疗可防止病变发展，改善预后。Objective To study the pathology and prognosis of pancreatic ductal papillary mucinous tumors. Methods 93 cases of pancreatic ductal papillary mucinous tumors undergoing excision in affiliated hospital of our college from February 2009 to January 2011 were retrospectively analyzed, including 51 cases of invasive cancer and 42 cases of non invasive cancer. The data of all patients was collected and analyzed, and the pathological characteristics and the operation effect of two groups were analyzed. Results The incidences of emaciation, CA199 〉37 U/ml, and skin and scleral staining in invasive group were significantly higher than those in non invasive group. The recurrence rate of invasive group was 41.18% （21/51）, significantly higher than 7.14% （3/42） of non invasive group; 5 year survival rate of invasive group was 56.86% （29/51）, significantly lower than 97.62% （41/42） of non invasive group, with statistically significant differences （P〈0.05）. Conclusions The prognosis of patients with non invasive pancreatic ductal papillary mucinous tumors is better after surgical treatment. Early surgical treatment can prevent the development of the disease and improve the prognosis.

关 键 词：病理特征 胰腺导管 乳头状黏液性肿瘤 预后 

分 类 号：R735.9[医药卫生—肿瘤]