胃癌肝转移的临床病理特征及危险因素分析  

Analysis on the clinicopathologic feature and risk factors of gastric cancer with hepatic metastasis

作　　者：吴超[1] 谢迪[1] 汪全新[1] 张保[1] 

机构地区：[1]湖北省红安县人民医院普外二科,438400

出　　处：《临床外科杂志》2016年第11期839-840,共2页Journal of Clinical Surgery

摘　　要：目的分析胃癌肝转移的临床病理特征和影响胃癌肝转移的危险因素。方法胃癌肝转移患者76例,收集患者患者性别、年龄、肝炎病史、原发灶直径、分化程度、淋巴结转移情况、血清癌胚抗原(CEA)、甲胎蛋白(AFP)、CA19-9、CA125水平等,无肝转移的胃癌患者76例作为对照组,Logistic多因素回归分析研究与胃癌肝转移相关的危险因素。结果原发灶直径、血清CEA水平、血清AFP水平、CA19-9水平与肝转移相关(P<0.05)。Logistic多因素回归分析显示,原发灶大小、血清CEA、AFP和CA19'9水平是胃癌肝转移的独立危险因素(P<0.05)。结论原发灶大小、血清CEA、AFP和CA19-9水平是胃癌肝转移的独立危险因素。Objective To analysis the clinicopathologic feature and risk factors of gastric cancer with hepatic metastasis. Methods The clinicopathological factors,such as gender,age,tumor size,tumor differntiation,lymph node metastasis and serum level of carcino-embryonic antigen（CEA）,α-fetoprotein （AFP）,CA19-9,CA125 were analysed in 76 cases with hepatic metastasis and 76 cases without hepatic metastasis who were served as the control group. Logistic multifactor regression was used to analysis the risk factors associated with gastric cancer with hepatic metastasis. Results The tumor size and serum lev-el of CEA,AFP,CA19-9 were statistically significant as risk factors for hepatic metastasis（P 〈 0. 05）. Lo-gistic regression analysis revealed that the independent risk factors of hepatic metastasis were the tumor size and serum level of CEA,AFP,CA19-9（P 〈 0. 05）. Conclusion The tumor size and serum level of CEA,AFP,CA19-9 were statistically significant risk factors of hepatic metastasis.

关 键 词：胃癌 肝转移 癌胚抗原 甲胎蛋白 

分 类 号：R735.2[医药卫生—肿瘤]