氩离子凝固术联合药物与单药治疗Barrett食管疗效比较的Meta分析  

Meta- analysis of comparison between APC combined with drug treatment and drug treatment alone in Barrett's esophagus

作　　者：杨春[1] 

机构地区：[1]东南大学附属南京同仁医院消化内科,江苏南京211100

出　　处：《包头医学院学报》2016年第12期147-149,共3页Journal of Baotou Medical College

摘　　要：目的:比较氩离子凝固(Argon plasma coagulation,APC)术联合药物治疗与单纯药物治疗对Barrett食管的疗效差异,为临床选择治疗方案提供依据。方法:通过计算机检索Pub Med、EMBASE、Cochrane Library、VIP、CNKI、万方等数据库,搜集从各数据库建库至2015年11月的相关文献。采用Meta分析方法对其中筛出的4篇符合要求的文献进行定量分析。结果:APC术联合药物治疗的有效率为86.3%,单纯药物治疗的有效率为61.8%,两种疗法加权合并率差均值为1.43,95%CI=(1.05,1.94),联合组患者的治疗总有效率高于单药组(P<0.05);两组患者的不良反应发生率对比差异无统计学意义。结论:APC术联合药物治疗的有效率高于单纯物药治疗。Objective： To compare therapeutic effects of argon plasma coagulation （ APC ） combined with drug treatment and drug treatment alone in Barrett＇s esophagus so as to optimize the clinical treatment measure. Methods： The pertinent literature was collected by searching the data- bases such as PubMed, EMBASE, the Cochrane Library, VIP, CNKI and Wan Fang from the establishment of these databases to November 2015. Meta -analysis was adopted for quantitative analysis of 4 papers which meet the requirements. Results：The care rate was 86.3% in the group of APC combined with drug treatment, and 61.8% in the group of drug treatment. The weighted overall mean quality score of the studies was 1.43 （95 % CI = 1.05,1.94）. The total effective rate in the APC combined with drug group was significantly higher than that in the drug treatment group （ P 〈 0.05 ）. There was no statistically significance in the incidence of adverse reactions between the two groups. Conclusion： The effective rate of method by combining APC with drug was higher than that by using drugs alone in the treatment of Barrett＇s esophagus.

关 键 词：BARRET食管 氩离子凝固术 药物治疗 META分析 

分 类 号：R571[医药卫生—消化系统]