中国人群饮水类型与结直肠癌患病风险的Meta分析  

Relationship between Drinking Water Type and Colorectal Cancer in China: a Meta-analysis

作　　者：杨文静[1] 董梦萌 闫旭[1] 王媛媛[1] 窦燕生[1] 史黎薇[1] 

机构地区：[1]中国疾病预防控制中心环境与健康相关产品安全所

出　　处：《环境卫生学杂志》2016年第5期337-341,共5页JOURNAL OF ENVIRONMENTAL HYGIENE

基　　金：淮河流域重点地区癌症综合防治项目(国家卫生计划生育委员会资助)

摘　　要：目的探究饮用水类型与结直肠癌患病风险的关系。方法收集国内外饮用水类型与结直肠癌发病关系的文献,应用Meta分析方法对上述研究进行异质性检验和效应值合并,并进行亚组分析和敏感性分析。结果饮用自来水和井水与结直肠癌无关联性,其合并OR/RR值及95%CI分别是0.86[0.63,1.19],0.49[0.18,1.13]。饮用地表水是结直肠癌发生的危险因素,其合并OR/RR值及95%CI为2.59[1.05,6.37]。结论饮用地表水是结直肠癌的可能致癌因素之一。Objective To evaluate the relationship between the type of drinking water and the incidence of colorectal cancer. Methods All literatures on the relationship between the type of drinking water and the incidence of colorectal cancer were collected. Meta-analysis method was used to conduct heterogeneity test and the effect value combination,and to conduct group analysis and sensitivity analysis. Results No association between drinking tap water / well water and colorectal cancer was found,the tap and well water overall summary of OR / RR and 95 % CI were 0. 86 [0. 63,1. 19 ],0. 49 [0. 18,1. 13]respedively. Drinking surface water was significantly associated with an increase of colorectal cancer risk,the overall summary was OR / RR = 2. 59 [1. 05,6. 37].Conclusion Drinking surface water was probably one of carcinogenic factors for colorectal cancer.

关 键 词：结直肠癌 饮水 META分析 

分 类 号：R735.3[医药卫生—肿瘤]