鉴定角膜缘干细胞缺乏方法的研究进展  

Review of the method of identifying limbal stem cell deficiency

作　　者：兰梅[1,2] 杨芳[1] 余锦强[1] 

机构地区：[1]湖北医药学院附属人民医院眼科,中国湖北省十堰市442000 [2]中国湖北省十堰市人民医院临床医学研究所,442000

出　　处：《国际眼科杂志》2017年第1期59-61,共3页International Eye Science

基　　金：十堰市科学技术研究与开发项目资金(No.2010-014z)~~

摘　　要：角膜缘干细胞缺乏引起的角膜疾病是眼科门诊较为常见的疾病,角膜缘干细胞移植已成为治疗该疾病的研究热点。根据角膜缘干细胞是否缺乏以及角膜缘干细胞的缺乏程度,选择的干细胞治疗方式不同。因此鉴定角膜缘干细胞缺乏是选择移植手术的重要依据,能够为后续移植实验奠定坚实的基础。本文主要总结了近年来鉴定角膜缘干细胞缺乏方法的研究进展。Corneal diseases caused by limbal stem cell deficiency are common in ophthalmology outpatients. Limbal stem cell transplantation has become a hot spot in the treatment of these diseases. According to limbal stem cell deficiency or not and its degree, we choose different cell therapy. Therefore, identification of limbal stem cell deficiency is an important reference for transplant surgery selection, which also could lay a solid foundation for the follow-up transplantation experiment. Here we mainly summarize some research advancement of identifying limbal stem cell deficiency methods.

关 键 词：角膜缘干细胞缺乏 印迹细胞学 免疫组化 光学相干断层扫描 活体共聚焦显微镜 

分 类 号：R772.2[医药卫生—眼科]