^(18)F-FDG符合线路显像在直肠癌术后局部复发中的诊断价值  

Diagnostic value of ^(18)F-FDG dual head gamma- camera coincidence in the local recurrence diagnosis of postoperative rectal carcinoma

作　　者：张伟晓 许小飞[1] 盛丹丹[1] 王成[1] 周玲玲[1] 刘雅洁[1] 

机构地区：[1]南京医科大学第二附属医院核医学科,江苏南京210011

出　　处：《现代肿瘤医学》2017年第1期79-81,共3页Journal of Modern Oncology

摘　　要：目的:评价^(18)F-FDG符合线路显像诊断直肠癌术后复发的价值,并与CT结果比较。方法:27例直肠癌术后患者,经病理活检或临床随访证实为术后复发者15例,无复发者12例。所有患者行^(18)F-FDG符合线路显像及CT平扫或增强,分析两种方法的诊断效能。结果:本研究中^(18)F-FDG符合线路显像诊断直肠癌术后复发的阳性预测值及准确性(93.3%、92.6%)均高于CT(86.7%、88.9%),但两者诊断的阴性预测值无明显差异(91.7%、91.7%)。27例患者均行CEA测定,15例CEA阳性患者中9例术区病变有FDG代谢,病理或随访证实该9例患者均为复发。12例CEA阴性患者中有3例患者术后局部有软组织密度影且FDG代谢明显增高。结论:^(18)F-FDG符合线路显像是诊断直肠癌术后局部复发敏感而有效的方法,值得临床推广应用。Objective： To evaluate the diagnostic value of^18F- FDG dual head gamma- camera coincidence（ DHC） imaging in the local recurrence of postoperative rectal cancer. Methods： DHC was studied between November2013 and April 2015 on 27 patients（ 9 women,18 men,mean age： 55. 6 years old） highly suspected recurrence. DHC imaging and contrast- enhanced computed tomography（ CT） findings were compared with histopathological findings and / or clinical follow- up data as the ＂ gold standard＂. Results： The positive predictive value and accuracy of DHC imaging（ 93. 3%,92. 6%） was higher than CT（ 86. 7%,88. 9%）. While the negative predictive value between the two imaging had no significant difference. All of the 27 cases were performed CEA measurement,9 cases of 15 CEA positive patients and 3 cases of the 12 CEA negative patients had FDG metabolism,confirmed by pathology and follow- up. Conclusion：^18F- FDG dual head gamma- camera coincidence（ DHC） imaging is a sensitive and effective method in the local recurrence diagnosis of postoperative rectal carcinoma,and has broad clinical application prospects.

关 键 词：^18F-FDG符合线路显像 直肠癌 复发 诊断 

分 类 号：R735.37[医药卫生—肿瘤] R730.4[医药卫生—临床医学]