忍冬叶化学成分的研究进展  

Research advances on chemical constituents of leaves from Lonicera japonica Thunb.

作　　者：朱姮 陈静娴[2] 文蕾[1] 王召平[1] 井凤[3] 王岱杰[3] ZHU Heng CHEN Jing - xian WEN Lei WANG Zhao- ping JING Feng WANG Dai- jie(School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China School of Life Sciences, Shandong Normal University, Jinan 250014, China Shandong Provincial Key Laboratory of Traditional Chinese Medicine Quality Control Technology, Shandong Analysis and Test Center, Jinan 250014, China)

机构地区：[1]山东中医药大学药学院,山东济南250355 [2]山东师范大学生命科学学院,山东济南250014 [3]山东省中药质量控制技术重点实验室,山东省分析测试中心,山东济南250014

出　　处：《山东科学》2016年第6期30-39,共10页Shandong Science

基　　金：山东省科技发展计划(2014GSF119031)

摘　　要：忍冬叶为金银花采摘后的副产物,产量约为花的10倍,且具有较强的药理活性。本文对忍冬叶中挥发油类、有机酸类、黄酮类以及环烯醚萜苷类等化学成分进行综述,发现忍冬叶中的化学成分与金银花相似,在目前药材市场上金银花价格居高不下的情况下,可以考虑作为金银花的替代品。目前对忍冬叶的研究热点主要集中在含量测定、成分分离及提取物药理研究方面,今后应开展对忍冬叶系统的化学分离及基于活性导向的活性部位研究,同时与列入药典的金银花和忍冬藤进行同类药理活性的比较研究。Leaves from Lonicera japonica Thunb. are by-products of Lonicerae japonicae flos,about 10 times yield of flowers, and have stronger pharmacological activity. We review chemical constituents of volatile oil, organic acids, flavonoids and iridoid glycosides in leaves of Lonicera japonica and discover that these are similar with those of the flowers. Therefore, the leaves can serve as substitutes for Lonicerae japonicae flos for it＇s existing high prices. Their research focus lies in content determination, component separation and pharmacology of extracts. Their future research should highlight chemical separation and activity oriented active sites, and comparison of pharmacological activity between leaves and flowers from Lonicera japonica Thunb.

关 键 词：忍冬 忍冬叶 化学成分 

分 类 号：R284.2[医药卫生—中药学]