2014年山西省碘缺乏病病情监测结果分析  

An analysis of monitoring data of iodine deficiency disorders in Shanxi Province in 2014

作　　者：王永平[1] 贾清珍[1] 王三祥[2] 张向东[1] 郭百锁[1] 张峰峰[3] 王正辉[2] 李军[2] 程晓天[3] 吴赵明[2] 任艳婷[1] 

机构地区：[1]山西省地方病防治研究所碘缺乏病克山病研究室,临汾041000 [2]山西省地方病防治研究所大骨节病、氟中毒、砷中毒研究室,临汾041000 [3]山西省地方病防治研究所检验科,临汾041000

出　　处：《中华地方病学杂志》2016年第12期896-900,共5页Chinese Journal of Endemiology

基　　金：中央补助地方重大公共卫生服务地方病防治项目（2014）;志谢所有参与此次调查工作的各项目单位工作人员

摘　　要：目的了解山西省食盐碘含量调整后居民碘缺乏病病情及碘营养现况，评估碘营养改善效果。方法2014年在山西省按“人121比例概率抽样（population proportion sampling,PPS）方法”确定30个县（市、区），采取单纯随机抽样方法从每个县（市、区）中抽取1所小学，每所小学抽取50名8—10岁儿童（男、女各半），进行甲状腺检测，同时采集尿样和家中盐样。甲状腺检测采用B超法，尿碘测定采用砷铈催化分光光度法（WS／T107．2006），盐碘测定采用直接滴定法。同时，在每所小学所在乡（镇、街道办事处）抽取20名孕妇，进行尿碘含量测定。对比2011年盐碘含量调整前的历史资料，评估山西省盐碘含量调整效果。结果共检测居民食用盐1437份，盐碘中位数为24．1mg／kg，以新标准（18-33mg／kg）计，碘盐覆盖率为95．4％（1371／1437），碘盐合格率为80．3％（1101／1371），合格碘盐食用率为76．6％（1101／1437）。共检测儿童尿样1496份、孕妇尿样630份，尿碘中位数分别为224．6、177．1μg/L，均明显低于2011年的274．6、279．6μg／L，二者比较差异均有统计学意义（H=70．10、153．50，P均〈0．05）。儿童和孕妇尿碘处于碘适宜水平的调查县（市、区）所占比例分别为36．7％（11／30）、56．7％（17／30），均高于2011年的6．5％（2／31）、25．8％（8／31），二者比较差异均有统计学意义（χ2=7．88、5．00，P均〈0．05）。共对8～10岁儿童1552人进行甲状腺检查，甲状腺肿大（简称甲肿）69人，甲肿率为4-4％。结论新标准含量碘盐能够保证山西省碘缺乏病处于持续消除状态，并且使以学龄儿童为代表的一般人群及以孕妇为代表的重点人群碘营养更加合理。Objective To master the iodine nutritional status of residents and to evaluate the effect of iodine nutrition improvement on residents health after the adjustment of salt iodine concentration. Methods According to the method of population proportion sampling, 30 county-level monitoring sites were selected in 2014, a primary school was selected from each county （city, district） by the method of simple random sampling and 50 students aged 8 - 10 （half males and half females） were selected in each school, B ultrasound was used to detect thyroid volume, arsenic cerium catalytic spectrophotometry （WS/T 107-2006） was used to detect urinary iodine, direct titration was used to detect salt iodine; At the same time, 20 pregnant women were selected from each town and urinary iodine was determined. All results were compared with the results of 2011 to evaluate the effect of iodine nutrition improvement on resident＇s health after the adjustment of salt iodine concentration. Results A total of 1 437 edible salt samples were tested, the median of salt iodine concentration was 24.1 mg/kg. Based on the newstandard （18 - 33 mg/kg）, the coverage rate of iodized salt was 95.4% （1 371/1 437）, the qualified rate of iodized salt was 80.3% （1 101/1 371）, the consumption rate of qualified iodized salt was 76.6% （1 101/1 437）. A total of 1 496 urine samples of children and 630 urine samples of pregnant women were tested, the median of urinary iodine of children and pregnant women was 224.6 and 177.1 μg/L, respectively, which were significantly lower than those of 2011 （274.6, 1279.6 μg/L）, the differences were statistically significant （H = 70.10, 153.50, all P 〈 0.05）. The proportion of counties which iodine nutrition of children and pregnant women in suitable range was 36.7% （11/30） and 56.7% （17/30）, which were higher than those of 2011 [6.5% （2/31）, 25.8% （8/31）], the differences were statistically significant （χ2 = 7.88, 5.00, all P 〈 0.05）. Totally 1 552 children were

关 键 词：碘 盐类 尿 甲状腺 营养 

分 类 号：R599[医药卫生—内科学]