舍曲林联合结构式家庭治疗老年抑郁症的疗效观察  

CLINICAL OBSERVATION OF SERTRALINE COMBINED WITH STRUCTURAL FAMILY THERAPY IN THE TREATMENT OF SENILE DEPRESSION

作　　者：石捷[1] 戴剑[1] 陶建青[1] 曹译丹[1] 梁佳[1] 康红[1] 黄玲[1] 

机构地区：[1]广西壮族自治区人民医院心理康复中心,南宁530022

出　　处：《广西医科大学学报》2016年第6期1006-1009,共4页Journal of Guangxi Medical University

基　　金：广西医药卫生自筹经费计划课题资助项目(No.Z2015347)

摘　　要：目的:探讨舍曲林联合结构式家庭治疗老年抑郁症的临床疗效。方法:选取2014年11月至2015年11月广西壮族自治区人民医院心理康复中心收治的104例老年抑郁症患者,按数字表法将其随机分为观察组和对照组,每组52例。对照组组患者给予舍曲林治疗,观察组患者在此治疗基础上,同时联合结构式家庭治疗;疗程均为8周。观察比较两组患者汉密尔顿抑郁量表(HAMD-17)评分、日常生活能力表(ADL)评分及幸福进取者问卷(HEIQ)评分变化、不良反应以及6个月病情复发率。结果:两组患者治疗前HAMD-17评分、ADL评分及HEIQ评分比较,差异均无统计学意义(均P>0.05);治疗后,两组患者HAMD-17评分、ADL评分均较治疗前显著降低(均P<0.01),而HEIQ评分较治疗前显著升高(P<0.01),且观察组患者HAMD-17评分、ADL评分及HEIQ评分改善程度均明显优于对照组(均P<0.01)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。观察组患者6个月病情复发率较对照组少,两组比较差异有统计学意义(P<0.05)。结论:舍曲林联合结构式家庭治疗老年抑郁症患者,能有效消除或缓解患者的临床症状,提高其生活适应能力,较好地改善患者的生活质量。Objective：To evaluate the clinical efficacy of sertraline combined with structural family therapy in the treatment of senile depression. Methods： 104 cases of elderly patients with depression in our hospital from November 2014 to November 2015 were selected and were randomly divided into a control group and an observation group. The patients in the control group received sertraline treatment, and those in the ob- servation group received sertraline combined structural family therapy. All patients received 8 weeks of treatment. The Hamilton depression scale （HAMD-17） scores, activity of daily living （ADL） score and the happy enterprising individual questionnaire （HEIQ） score, incidence of adverse reactions and recurrence rate in both groups were compared. Results： There were no significant differences between the two groups in the scores of HAMD-17, ADL and HEIQ （ P 〉0. 05）. After treatment, HAMD-17 scores and ADI. scores of two groups were significantly lower than those before treatment （ P 〈0.01）, while HEIQ score was significantly higher than that before treatment （ P 〈0.01）. The scores of HAMD-17, ADL and HEIQ in the observation group were better than those in the control group （ P 〈0.01）. There was no significant difference in the rence rate in the traline combined incidence of adverse reactions between the two groups （ P 〉0.05）. The 6-month recur observation group was lower than that in the control group （ P 〈0.05）. Conclusion： Serwith structural family therapy could effectively eliminate or relieve senile depression, and improve patients＇ life adaptability and quality.

关 键 词：老年抑郁症 舍曲林 结构式家庭治疗 

分 类 号：R749.4[医药卫生—神经病学与精神病学]